Chemokines are an indispensable component of our immune system through the regulation
of directional migration and activation of leukocytes. CXCL8 is the most potent human …

Cells have the ability to respond to various types of environmental cues, and in many cases
these cues induce directed cell migration towards or away from these signals. How cells …

The neurotransmitter dopamine is a key factor in central nervous system (CNS) function,
regulating many processes including reward, movement, and cognition. Dopamine also …

The contribution of CD4+ T cells to protective or pathogenic immune responses to SARS-
CoV-2 infection remains unknown. Here, we present single-cell transcriptomic analysis of> …

Chronic (continuous, non-interrupted) hypoxia and cycling (intermittent, transient) hypoxia
are two types of hypoxia occurring in malignant tumors. They are both associated with the …

Interleukin-10 (IL-10) is a pleiotropic cytokine that has a fundamental role in modulating
inflammation and in maintaining cell homeostasis. It primarily acts as an anti-inflammatory …

The chemokine ligand CCL2 and its receptor CCR2 are implicated in the initiation and
progression of various cancers. CCL2 can activate tumour cell growth and proliferation …

Abstract Novel coronavirus disease 2019 (COVID-19) has resulted in a global pandemic
and is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Several …

Stroke, the third leading cause of death and disability worldwide, is undergoing a change in
perspective with the emergence of new ideas on neurodegeneration. The concept that …

CC chemokines, a subfamily of 27 chemotactic cytokines, are a component of intercellular
communication, which is crucial for the functioning of the tumor microenvironment. Although …