Selenium as a bioactive micronutrient in the human diet and its cancer chemopreventive activity

D Radomska, R Czarnomysy, D Radomski… - Nutrients, 2021 - mdpi.com
This review answers the question of why selenium is such an important trace element in the
human diet. Daily dietary intake of selenium and its content in various food products is …

Ebselen and analogues: Pharmacological properties and synthetic strategies for their preparation

C Santi, C Scimmi, L Sancineto - Molecules, 2021 - mdpi.com
Ebselen is the leader of selenorganic compounds, and starting from its identification as
mimetic of the key antioxidant enzyme glutathione peroxidase, several papers have …

Antitumor effects of selenium

SJ Kim, MC Choi, JM Park, AS Chung - International Journal of Molecular …, 2021 - mdpi.com
Functions of selenium are diverse as antioxidant, anti-inflammation, increased immunity,
reduced cancer incidence, blocking tumor invasion and metastasis, and further clinical …

A diselenium-bridged covalent organic framework with pH/GSH/photo-triple-responsiveness for highly controlled drug release toward joint chemo/photothermal …

H Lou, L Chu, W Zhou, J Dou, X Teng, W Tan… - Journal of Materials …, 2022 - pubs.rsc.org
Here, a novel joint chemo/photothermal/chemodynamic therapy was developed using a
pH/GSH/photo triple-responsive 2D-covalent organic framework (COF) drug carriers for …

Covalent organic framework nanoparticles: Overcoming the challenges of hypoxia in cancer therapy

N Singh, M Won, Y Xu, C Yoon, J Yoo, M Li… - Coordination Chemistry …, 2024 - Elsevier
Hypoxia, or low oxygen levels, is a common feature of the tumor microenvironment. It is
caused by the aggressive proliferation of cancer cells, which consume more oxygen than …

[HTML][HTML] Metal-based compounds containing selenium: An appealing approach towards novel therapeutic drugs with anticancer and antimicrobial effects

S Ramos-Inza, D Plano, C Sanmartin - European Journal of Medicinal …, 2022 - Elsevier
In recent years, both metal-based complexes and selenium-containing compounds have
been widely explored for their therapeutic properties due to their roles in biological …

Pro-apoptotic activity of bioactive compounds from seaweeds: promising sources for developing novel anticancer drugs

R Agena, A de Jesús Cortés-Sánchez… - Marine Drugs, 2023 - mdpi.com
The process by which cancer cells evade or inhibit apoptosis is considered one of the
characteristics of cancer. The ability of cancer cells to escape apoptosis contributes to tumor …

Enantioselective Selenol-ene Using Rh-Hydride Catalysis

HS Slocumb, S Nie, VM Dong… - Journal of the American …, 2022 - ACS Publications
This study showcases the first enantioselective hydroselenation of styrenes.
Organoselenium building blocks are accessed with selectivity for the branched isomer …

Organic selenocompounds: are they the panacea for human illnesses?

PA Nogara, ME Pereira, CS Oliveira, L Orian… - New Journal of …, 2023 - pubs.rsc.org
The selenium element is essential to some life forms and its biological-chemistry function is
mainly performed by the selenol/selenolate moiety (–SeH/–Se–) in a few selenoproteins …

[HTML][HTML] Role of selenium in type 2 diabetes, insulin resistance and insulin secretion

P Casanova, D Monleon - World journal of diabetes, 2023 - ncbi.nlm.nih.gov
Selenium is a trace mineral essential for life that acts physiologically through selenoproteins.
Among other actions, the endogenous antioxidant selenoprotein glutathione peroxidase and …