Computational evaluation of the inhibitory potential of some urea, thiourea, and selenourea derivatives of diselenides against leishmaniasis: 2D-QSAR …

FA Ugbe, EI Edache, SE Adeniji, DE Arthur… - Journal of Molecular …, 2024 - Elsevier
Leishmaniasis affects more than twelve million people globally and a further one billion
people are at risk in leishmaniasis endemic areas. The lack of a vaccine for leishmaniasis …

Pharmaceutical and safety profile evaluation of novel selenocompounds with noteworthy anticancer activity

MA Marć, E Domínguez-Álvarez, G Latacz… - Pharmaceutics, 2022 - mdpi.com
Prior studies have reported the potent and selective cytotoxic, pro-apoptotic, and
chemopreventive activities of a cyclic selenoanhydride and of a series of selenoesters …

Selenium-incorporated mesoporous silica nanoparticles for osteosarcoma therapy

L He, P Habibovic, S van Rijt - Biomaterials Science, 2023 - pubs.rsc.org
Selenium (Se) compounds are promising chemotherapeutics due to their ability to inhibit
cancer cell activity via the generation of reactive oxygen species (ROS). However, to …

Organoselenium compounds as functionalizing agents for gold nanoparticles in cancer therapy

S Lorenzoni, S Cerra, E Angulo-Elizari… - Colloids and Surfaces B …, 2022 - Elsevier
Gold nanoparticles (AuNPs) modified with four organoselenium compounds, ie, 4-
selenocyanatoaniline (compound 1), 4, 4′-diselanediyldianiline (compound 2), N-(4 …

Biogenic synthesized SeONPs by Bacillus paramycoides as antimicrobial, anticancer, antioxidant, apoptotic and hepatorenal treating agent.

HA El Refai, SIA Mohamed, AFA Naser… - Biocatalysis and …, 2024 - Elsevier
Employing bacteria in nanoparticles (NPs) biosynthesis has appeared as a fast-emerging
research area in green nanotechnology applications. The biosynthesis processes …

Organoselenocyanates tethered methyl anthranilate hybrids with promising anticancer, antimicrobial, and antioxidant activities

B Al-Abdallah, YS Al-Faiyz, S Shaaban - Inorganics, 2022 - mdpi.com
Novel methyl anthranilate-based organoselenocyanate hybrids were developed, and their
structures were confirmed by the state-of-the-art spectroscopic techniques. Their …

Using chitosan-stabilized, hyaluronic acid-modified selenium nanoparticles to deliver CD44-targeted PLK1 siRNAs for treating bladder cancer

M Shahidi, O Abazari, P Dayati, JZ Reza… - …, 2023 - Taylor & Francis
Aims: Achieving an effective biocompatible system for siRNAs delivery to the tumor site
remains a significant challenge. Materials & methods: Selenium nanoparticles (SeNPs) …

Selenium Modification of Natural Products and Its Research Progress

K Cheng, Y Sun, B Liu, J Ming, L Wang, C Xu, Y Xiao… - Foods, 2023 - mdpi.com
The selenization of natural products refers to the chemical modification method of artificially
introducing selenium atoms into natural products to interact with the functional groups in the …

Glutathione peroxidase mimics based on conformationally-restricted, peri-like, 4, 5-disubstituted fluorene dichalcogenides

K Jagdev, D Tanini, JW Lownes, C Figliola… - Organic & …, 2021 - pubs.rsc.org
Glutathione peroxidase (GPx) regulates cellular peroxide levels through glutathione
oxidation. GPx-mimics based on 4, 5-disubstituted fluorene diselenides, their oxides, and …

Antiproliferative Effect of Inorganic and Organic Selenium Compounds in Breast Cell Lines

NS da Costa, LS Lima, FAM Oliveira, MEA Galiciolli… - Biomedicines, 2023 - mdpi.com
Triple-negative breast cancer (TNBC) is an aggressive, fast-growing tumor that is more likely
to spread to distant organs. Among women diagnosed with breast cancer, the prevalence of …