Applications of Pyrrole and Pyridine-based Heterocycles in Cancer Diagnosis and Treatment

R Tyagi, K Yadav, N Srivastava… - Current Pharmaceutical …, 2024 - ingentaconnect.com
Background: The escalation of cancer worldwide is one of the major causes of economy
burden and loss of human resources. According to the American Cancer Society, there will …

Selenium-containing agents acting on cancer—a new hope?

S Garbo, S Di Giacomo, D Łażewska… - Pharmaceutics, 2022 - mdpi.com
Selenium-containing agents are more and more considered as an innovative potential
treatment option for cancer. Light is shed not only on the considerable advancements made …

Bioinorganic modulators of ferroptosis: a review of recent findings

A Bartos, J Sikora - International Journal of Molecular Sciences, 2023 - mdpi.com
Ferroptosis was first reported as a separate modality of regulated cell death in 2008 and
distinguished under its current name in 2012 after it was first induced with erastin. In the …

Unexpected kinetically controlled organoselenium-based isomaleimide: X-ray structure, hirshfeld surface analysis, 3D energy framework approach, and density …

S Shaaban, H Ferjani, HM Abd El-Lateef… - Frontiers in …, 2022 - frontiersin.org
Reduction of 4, 4′-diselanediyldianiline (1) followed by the reaction with bromo-4-
(bromomethyl) benzene afforded the corresponding 4-((4-bromobenzyl) selanyl) aniline (2) …

Varied effect of fortification of kale sprouts with novel organic selenium compounds on the synthesis of sulphur and phenolic compounds in relation to cytotoxic …

P Pasko, A Galanty, P Zagrodzki, P Zmudzki, U Bieniek… - 2022 - digital.csic.es
Selenium deficiency in daily diet is a common problem in many countries, thus searching for
new dietary sources of this trace element is an important scientific challenge. Selenium …

Sodium selenite increases drought tolerance by promoting jasmonic acid biosynthesis in cucumber

D Wen, Y Zheng, Y Han, J Song, S Sun, N Yang… - Horticulture …, 2023 - Springer
Jasmonic acid (JA) is an important and widely distributed plant hormone. However, the
molecular and physiological mechanism of JA in improving drought tolerance in response to …

Seleno-metabolites and their precursors: a new dawn for several illnesses?

C Morán-Serradilla, E Angulo-Elizari… - Metabolites, 2022 - mdpi.com
Selenium (Se) is an essential element for human health as it is involved in different
physiological functions. Moreover, a great number of Se compounds can be considered …

Oxidative Stress and Chronic Myeloid Leukemia: A Balance between ROS-Mediated Pro-and Anti-Apoptotic Effects of Tyrosine Kinase Inhibitors

A Allegra, G Mirabile, S Caserta, F Stagno, S Russo… - Antioxidants, 2024 - mdpi.com
The balanced reciprocal translocation t (9; 22)(q34; q11) and the BCR-ABL fusion gene,
which produce p210 bcr-abl protein production with high tyrosine kinase activity, are …

Unveiling the Chemical Composition, Bioactive Profile and Antioxidant Capacity of Dried Egyptian Jew's Mallow Stems as a Promising Anticancer Agent

MR Ali, HH Ibrahim, AA Salah-Eldin - Molecules, 2024 - mdpi.com
Phytochemicals from waste materials generated by agricultural and industrial processes
have become globally significant due to their accessibility and potential effectiveness with …

Novel N,N′-Disubstituted Selenoureas as Potential Antioxidant and Cytotoxic Agents

G Calvo-Martín, D Plano, I Encío, C Sanmartín - Antioxidants, 2021 - mdpi.com
A series of 30 novel N, N disubstituted selenoureas were synthesized, characterized, and
their antioxidant ability was tested using 2, 2-diphenyl-1-picrylhydrazyl (DPPH) and 2, 2 …