Emerging strategies for combating Fusobacterium nucleatum in colorectal cancer treatment: Systematic review, improvements and future challenges
H Liu, Y Yu, A Dong, M Elsabahy, YW Yang… - Exploration, 2024 - Wiley Online Library
Colorectal cancer (CRC) is generally characterized by a high prevalence of Fusobacterium
nucleatum (F. nucleatum), a spindle‐shaped, Gram‐negative anaerobe pathogen derived …
nucleatum (F. nucleatum), a spindle‐shaped, Gram‐negative anaerobe pathogen derived …
Nano-enabled colorectal cancer therapy
Q Pan, X Fan, L Xie, D Wu, R Liu, W Gao, K Luo… - Journal of Controlled …, 2023 - Elsevier
Colorectal cancer (CRC), one of the most common and deadliest diseases worldwide, poses
a great health threat and social burden. The clinical treatments of CRC encompassing …
a great health threat and social burden. The clinical treatments of CRC encompassing …
Transforming intratumor bacteria into immunopotentiators to reverse cold tumors for enhanced immuno-chemodynamic therapy of triple-negative breast cancer
Immunotherapy of triple-negative breast cancer (TNBC) has an unsatisfactory therapeutic
outcome due to an immunologically “cold” microenvironment. Fusobacterium nucleatum (F …
outcome due to an immunologically “cold” microenvironment. Fusobacterium nucleatum (F …
Targeting Vascular Destruction by Sonosensitizer‐Free Sonocatalytic Nanomissiles Instigates Thrombus Aggregation and Nutrition Deprivation to Starve Pancreatic …
Y He, T Wang, Y Song, C Fang, Y Wang… - Advanced Functional …, 2024 - Wiley Online Library
Sonosensitizers in current sonodynamic therapy (SDT) often suffer from poor delivery
efficiency, phototoxicity, and disputed safety. To overcome these issues, a sonosensitizers …
efficiency, phototoxicity, and disputed safety. To overcome these issues, a sonosensitizers …
A bodipy‐based aggregation‐induced emission nanoagent for sonodynamic antibacterial studies
Y Xu, D Tang, L Li, X Li, Q Chang… - Advanced Functional …, 2024 - Wiley Online Library
Sonodynamic therapy (SDT) has demonstrated significant potential in addressing multidrug‐
resistant bacterial infections due to its noninvasive nature and independence from …
resistant bacterial infections due to its noninvasive nature and independence from …
Intratumoral Microbiota as a Target for Advanced Cancer Therapeutics
F Peng, M Hu, Z Su, L Hu, L Guo, K Yang - Advanced Materials, 2024 - Wiley Online Library
In recent years, advancements in microbial sequencing technology have sparked an
increasing interest in the bacteria residing within solid tumors and its distribution and …
increasing interest in the bacteria residing within solid tumors and its distribution and …
A GSH‐Responsive Prodrug with Simultaneous Triple‐Activation Capacity for Photodynamic/Sonodynamic Combination Therapy with Inhibited Skin Phototoxicity
C Deng, J Zhang, F Hu, S Han, M Zheng, F An, F Wang - Small, 2024 - Wiley Online Library
Herein, a dual‐sensitizer prodrug, named pro‐THPC, has been designed to function as both
a photosensitizer and a sonosensitizer prodrug for precise antitumor combination therapy …
a photosensitizer and a sonosensitizer prodrug for precise antitumor combination therapy …
Recent progress in nanomaterials for bacterial-related tumor therapy
Many studies suggest that tumor microbiome closely relates to the oncogenesis and anti-
tumor responses in multiple cancer types (eg, colorectal cancer (CRC), breast cancer, lung …
tumor responses in multiple cancer types (eg, colorectal cancer (CRC), breast cancer, lung …
Drug delivery systems for enhanced tumour treatment by eliminating intra-tumoral bacteria
Z Liu, Y Ma, J Ye, G Li, X Kang, W Xie… - Journal of Materials …, 2024 - pubs.rsc.org
Cancer remains one of the serious threats to human health. The relationship between
bacteria and various tumours has been widely reported in recent years, and studies on intra …
bacteria and various tumours has been widely reported in recent years, and studies on intra …
Fusobacterium nucleatum carcinogenesis and drug delivery interventions
Z Chen, L Huang - Advanced Drug Delivery Reviews, 2024 - Elsevier
The microbiome has emerged as a significant biomarker and modulator in cancer
development and treatment response. Recent research highlights the notable role of …
development and treatment response. Recent research highlights the notable role of …