Sepsis is a common and lethal syndrome: although outcomes have improved, mortality
remains high. No specific anti-sepsis treatments exist; as such, management of patients …

Estrogen has a plethora of effects in the cardiovascular system. Studies of estrogen and the
heart span human clinical trials and basic cell and molecular investigations. Greater …

Introduction Preclinical data indicate that oestrogen appears to play a beneficial role in the
pathophysiology of and recovery from critical illness. In few previous epidemiologic studies …

Abstract Background Coronavirus Disease 2019 (COVID-19) is a multi-systemic infection
caused by the novel Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), that …

The majority of injury combinations in multiply injured patients entail the chest, abdomen,
and extremities. Numerous pig models focus on the investigation of posttraumatic …

Although in-hospital mortality rates for sepsis have decreased, survivors often experience
lasting physical and cognitive deficits. Moreover, older adults are more vulnerable to long …

Background Pyogenic liver abscess (PLA) in the elderly is insufficiently elucidated. A few
studies attempted to investigate the role of age in PLA have yielded controversial results …

Objectives To develop and validate an individualized nomogram to predict probability of
patients with ureteral calculi developing into urosepsis. Methods The clinical data of 747 …

Intestinal ischemia reperfusion (IR)-induced tissue injury represents an acute inflammatory
response with significant morbidity and mortality. The mechanism of IR-induced injury is not …

Traumatic brain injury (TBI) is the leading cause of injury-related death and disability in
patients under the age of 46 years. Survivors of the initial injury often endure systemic …