[HTML][HTML] Fabrication of active targeting lipid nanoparticles: Challenges and perspectives

I Menon, M Zaroudi, Y Zhang, E Aisenbrey… - Materials Today Advances, 2022 - Elsevier
Targeted drug and gene delivery is the key for precision therapy. Lipid nanoparticles as non-
viral vectors have attracted extensive attentions in treating a variety of diseases, such as …

Nanomedicine embraces cancer radio-immunotherapy: mechanism, design, recent advances, and clinical translation

H Li, Q Luo, H Zhang, X Ma, Z Gu, Q Gong… - Chemical Society …, 2023 - pubs.rsc.org
Cancer radio-immunotherapy, integrating external/internal radiation therapy with immuno-
oncology treatments, emerges in the current management of cancer. A growing number of …

Nanoparticle‐Based Photothermal Therapy for Breast Cancer Noninvasive Treatment

Y Xiong, Y Rao, J Hu, Z Luo, C Chen - Advanced Materials, 2023 - Wiley Online Library
Rapid advancements in materials science and nanotechnology, intertwined with oncology,
have positioned photothermal therapy (PTT) as a promising noninvasive treatment strategy …

The mechanisms of anti-PEG immune response are different in the spleen and the lymph nodes

P Grenier, V Chénard, N Bertrand - Journal of Controlled Release, 2023 - Elsevier
Polyethylene glycol (PEG) is a common ingredient in nanomedicines and pharmaceuticals.
Recent studies show that approximately 20–70% of humans have anti-PEG antibodies that …

The interplay between PEGylated nanoparticles and blood immune system

C Guo, H Yuan, Y Wang, Y Feng, Y Zhang, T Yin… - Advanced Drug Delivery …, 2023 - Elsevier
During the last two decades, an increasing number of reports have pointed out that the
immunogenicity of polyethylene glycol (PEG) may trigger accelerated blood clearance …

Four ounces can move a thousand pounds: the enormous value of nanomaterials in tumor immunotherapy

Z Chen, Z Yue, K Yang, C Shen… - Advanced …, 2023 - Wiley Online Library
The application of nanomaterials in healthcare has emerged as a promising strategy due to
their unique structural diversity, surface properties, and compositional diversity. In particular …

Recent development of photoresponsive liposomes based on organic photosensitizers, Au nanoparticles, and azobenzene derivatives for nanomedicine

J Hu, D Wu, Q Pan, H Li, J Zhang… - ACS Applied Nano …, 2022 - ACS Publications
Photoresponsive liposomes are controlled-release liposomes modified by photoresponsive
materials. They use light with high spatial and temporal precision as a means of regulation …

Investigating generation of antibodies against the lipid nanoparticle vector Following COVID-19 vaccination with an mRNA vaccine

R Münter, E Sørensen, RB Hasselbalch… - Molecular …, 2023 - ACS Publications
Despite the success of mRNA-based vaccines against infectious diseases (including COVID-
19), safety concerns have been raised relating to the lipid nanoparticles (LNPs) used to …

Poly (2-oxazoline)-derived star-shaped polymers as potential materials for biomedical applications: A review

MN Leiske - European Polymer Journal, 2023 - Elsevier
Abstract Poly (2-oxazoline) s (POx) are a unique class of polymers with an enormous
potential for the preparation of functional materials. Their synthesis via the cationic ring …

Cancer-Associated Fibroblast Mimetic AIE Probe for Precision Imaging-Guided Full-Cycle Management of Ovarian Cancer Surgery

J Dai, H Ouyang, S Wei, B Chen, X Dong, J Hu… - Analytical …, 2023 - ACS Publications
Fluorescence imaging can improve surgical accuracy in ovarian cancer, but a high signal-to-
noise ratio is crucial for tiny metastatic cancers. Meanwhile, intraoperative fluorescent …