Two of the most prevalent human viruses worldwide, herpes simplex virus type 1 and type 2
(HSV-1 and HSV-2, respectively), cause a variety of diseases, including cold sores, genital …

The rapid development of two nucleoside-modified mRNA vaccines that are safe and highly
effective against coronavirus disease 2019 has transformed the vaccine field. The mRNA …

Summary Background Sexually transmitted infections (STIs) are a major public health issue
worldwide, but there is a paucity of literature on their burden and trends globally. We aimed …

Objective Sexually transmitted infections (STIs) are common worldwide and pose a
challenge to public health. We conducted this study to assess the annual incidence of five …

HSV-1 causes 50% of first-time genital herpes infections in resource-rich countries and
affects 190 million people worldwide. A prophylactic herpes vaccine is needed to protect …

Purpose: We aimed to review available data on the incidence of herpes simplex virus (HSV)
keratitis and other HSV ocular disease and to estimate the global burden of HSV ocular …

Genital herpes (GH) is caused by 2 related yet distinct viruses: herpes simplex viruses (HSV)
type-1 (HSV-1) and type-2 (HSV-2). 1 In 2016, there were an estimated 491.5 million people …

Background Herpes simplex virus type 2 (HSV-2) infection is a prevalent, sexually
transmitted infection with a sizable disease burden that is highest in sub-Saharan Africa …

Mucosal pathogens, as exemplified by severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2), human immunodeficiency virus (HIV) and Mycobacterium tuberculosis, lead …

Background Evidence suggests HSV-2 infection increases HIV acquisition risk and HIV/HSV-
2 coinfection increases transmission risk of both infections. We analysed the potential impact …