Summary Background Gram-negative Enterobacteriaceae with resistance to carbapenem
conferred by New Delhi metallo-β-lactamase 1 (NDM-1) are potentially a major global health …

Carbapenem‐resistant Enterobacteriaceae (CRE) have been listed by the WHO as high‐
priority pathogens owing to their high association with mortalities and morbidities …

In 2012, the European Centre for Disease Prevention and Control (ECDC) launched the
'European survey of carbapenemase-producing Enterobacteriaceae (EuSCAPE)'project to …

Plasmid-acquired carbapenemases in Enterobacteriaceae, which were first discovered in
Europe in the 1990s, are now increasingly being identified at an alarming rate. Although …

The emergence of one of the most recently described carbapenemases, namely, the New
Delhi metallo-lactamase (NDM-1), constitutes a critical and growingly important medical …

Background Not all patients infected with NDM-1-positive bacteria have a history of hospital
admission in India, and extended-spectrum β-lactamases are known to be circulating in the …

Over the past 10 years, dissemination of Klebsiella pneumoniae carbapenemase (KPC) has
led to an increase in the prevalence of carbapenem-resistant Enterobacteriaceae (CRE) in …

β-Lactamases, the enzymes that hydrolyze β-lactam antibiotics, remain the greatest threat to
the usage of these agents. In this review, the mechanism of hydrolysis is discussed for both …

Worldwide, bacterial resistance to chemical antibiotics has reached such a high level that
endangers public health. Presently, the adoption of alternative strategies that promote the …

β‐Lactam antibiotics are the most commonly used antibacterial agents and growing
resistance to these drugs is a concern. Metallo‐β‐lactamases are a diverse set of enzymes …