[HTML][HTML] Potential application of peripheral blood biomarkers in intracranial aneurysms

Y Wu, Z Zhao, S Kang, L Zhang, F Lv - Frontiers in Neurology, 2023 - frontiersin.org
Intracranial aneurysm (IA) counts are increasing yearly, with a high mortality and disability
after rupture. Current diagnosis and treatment rely on costly equipment, lacking effective …

[HTML][HTML] The markers and risk stratification model of intracranial aneurysm instability in a large Chinese cohort

Q Liu, K Li, H He, Z Miao, H Cui, J Wu, S Ding, Z Wen… - Science Bulletin, 2023 - Elsevier
Intracranial aneurysm is the leading cause of nontraumatic subarachnoid hemorrhage.
Evaluating the unstable (rupture and growth) risk of aneurysms is helpful to guild decision …

[HTML][HTML] Serum IL-1, pyroptosis and intracranial aneurysm wall enhancement: analysis integrating radiology, serum cytokines and histology

Q Liu, Y Zhang, C Zhu, W Liu, X Ma, J Chen… - Frontiers in …, 2022 - frontiersin.org
Background and Purpose Aneurysm wall enhancement (AWE) is correlated with the rupture
and growth risk of unruptured intracranial aneurysms (UIAs). Pyroptosis is a proinflammation …

Pro-inflammatory and anti-inflammatory cytokines levels are significantly altered in cerebrospinal fluid of unruptured intracranial aneurysm (UIA) patients

J Kamińska, M Maciejczyk, A Ćwiklińska… - Journal of …, 2022 - Taylor & Francis
Introduction Identifying all the relevant “players” in the formation and development of brain
aneurysms may help understand the mechanisms responsible for the formation of an …

Serum Interleukin-1 levels are associated with intracranial aneurysm instability

Q Liu, P Liu, Y Zhang, M Mossa-Basha… - Translational Stroke …, 2024 - Springer
Abstract Serum interleukin-1 (IL-1) are possibly indicative of the inflammation in the
intracranial aneurysm (IA) wall. This study aimed to investigate whether IL-1 could …

[HTML][HTML] The clinical significance of peripheral blood cell ratios in patients with intracranial aneurysm

HK Kim, KO Lee, SH Oh, KY Lee, SW Choo… - Frontiers in …, 2022 - frontiersin.org
Background and objective Inflammation is an important factor in the development of
aneurysm, and has been identified as a key characteristic predictive of rupture of intracranial …

Association of calcium channel blockers with lower incidence of intracranial aneurysm rupture and growth in hypertensive patients

Q Liu, J Li, Y Zhang, X Leng, M Mossa-Basha… - Journal of …, 2023 - thejns.org
OBJECTIVE Calcium channel blockers (CCBs) are antihypertensive agents with potential
vascular protection effects. This study investigated whether CCB usage was associated with …

[HTML][HTML] Association of select psychiatric disorders with incident brain aneurysm and subarachnoid hemorrhage among veterans

DL Cooke, H Shen, M Duvvuri, D Thompson… - Frontiers in Integrative …, 2023 - frontiersin.org
Background Brain aneurysms represent a significant cause of hemorrhagic stroke. Prior
research has demonstrated links between stress and stroke, including brain aneurysms. We …

[HTML][HTML] Neutrophil-to-lymphocyte ratio is associated with circumferential wall enhancement of unruptured intracranial aneurysm

XB Wu, JL Zhong, SW Wang, Y Su, PS Chen… - Frontiers in …, 2022 - frontiersin.org
Background and Purpose Neutrophil-lymphocyte ratio (NLR) predicts clinical outcomes in
patients with stroke. Aneurysm wall enhancement (AWE) on high-resolution vessel wall …

Low shear stress induces macrophage infiltration and aggravates aneurysm wall inflammation via CCL7/CCR1/TAK1/NF-κB axis

H Wei, G Wang, Q Tian, C Liu, W Han, J Wang, P He… - Cellular …, 2024 - Elsevier
Background This study aimed to elucidate the mechanism by which wall shear stress (WSS)
influences vascular walls, accounting for the susceptibility of intracranial aneurysms (IAs) to …