Atypical Hemolytic-Uremic Syndrome: Genetic Basis, Clinical Manifestations, and a Multidisciplinary Approach to Management
K Yerigeri, S Kadatane, K Mongan… - Journal of …, 2023 - Taylor & Francis
Hemolytic uremic syndrome (HUS) is a thrombotic microangiopathy (TMA) defined by the
triad of hemolytic anemia, thrombocytopenia, and acute kidney injury. Microthrombi develop …
triad of hemolytic anemia, thrombocytopenia, and acute kidney injury. Microthrombi develop …
[HTML][HTML] Thrombotic microangiopathy after kidney transplantation: an underdiagnosed and potentially reversible entity
A Ávila, E Gavela, A Sancho - Frontiers in Medicine, 2021 - frontiersin.org
Thrombotic microangiopathy is a rare but serious complication that affects kidney transplant
recipients. It appears in 0.8–14% of transplanted patients and negatively affects graft and …
recipients. It appears in 0.8–14% of transplanted patients and negatively affects graft and …
[HTML][HTML] Eculizumab rescue therapy in patients with recurrent atypical hemolytic uremic syndrome after kidney transplantation
C Duineveld, RN Bouwmeester, KL Wijnsma… - Kidney International …, 2023 - Elsevier
Introduction Since 2016, kidney transplantation in patients with atypical hemolytic uremic
syndrome (aHUS) in the Netherlands is performed without eculizumab prophylaxis …
syndrome (aHUS) in the Netherlands is performed without eculizumab prophylaxis …
[HTML][HTML] The role of genetic testing in the diagnostic workflow of pediatric patients with kidney diseases: the experience of a single institution
T Vaisitti, V Bracciamà, AC Faini, GM Brach Del Prever… - Human Genomics, 2023 - Springer
Purpose Inherited kidney diseases are among the leading causes of kidney failure in
children, resulting in increased mortality, high healthcare costs and need for organ …
children, resulting in increased mortality, high healthcare costs and need for organ …
New findings in preventing recurrence and improving renal function in AHUS patients after renal transplantation treated with eculizumab: a systemic review and meta …
ZC Tang, H Hui, C Shi, X Chen - Renal Failure, 2023 - Taylor & Francis
Background The long-term mortality of kidney transplantation patients with atypical
hemolytic uremic syndrome remains high, and the efficacy of the main treatment eculizumab …
hemolytic uremic syndrome remains high, and the efficacy of the main treatment eculizumab …
[HTML][HTML] “Eculizumab First” in the Management of Posttransplant Thrombotic Microangiopathy
F Maritati, V Corradetti, C Bini, M Provenzano… - Kidney International …, 2024 - Elsevier
Introduction Posttransplant thrombotic microangiopathy (PT-TMA) is an uncommon event
that characterizes approximately 3% to 14% of kidney transplants (KTs), and that is …
that characterizes approximately 3% to 14% of kidney transplants (KTs), and that is …
[HTML][HTML] Atypical HUS triggered by COVID-19: a case report
V Tiwari, G Bhandari, A Gupta, P Gupta… - Indian Journal of …, 2022 - journals.lww.com
We hereby present a case of an atypical hemolytic uremic syndrome (aHUS) precipitated by
coronavirus disease 2019 (COVID-19). A 26-year-old male was diagnosed with COVID-19 …
coronavirus disease 2019 (COVID-19). A 26-year-old male was diagnosed with COVID-19 …
Recurrent complement-mediated Hemolytic uremic syndrome after kidney transplantation
Hereditary forms of hemolytic uremic syndrome (HUS), formerly known as atypical HUS,
typically involve mutations in genes encoding for components of the alternative pathway of …
typically involve mutations in genes encoding for components of the alternative pathway of …
[HTML][HTML] Recommendations for the individualised management of atypical hemolytic uremic syndrome in adults
A Ávila, M Cao, M Espinosa, J Manrique… - Frontiers in …, 2023 - ncbi.nlm.nih.gov
Background Despite significant advances in therapeutic management of atypical hemolytic
uremic syndrome (aHUS), guidelines are not timely updated and achieving a consensus on …
uremic syndrome (aHUS), guidelines are not timely updated and achieving a consensus on …
[HTML][HTML] Unveiling the Incidence and Graft Survival Rate in Kidney Transplant Recipients With De Novo Thrombotic Microangiopathy: A Systematic Review and Meta …
CY Hsiung, HY Chen, SH Wang… - Transplant …, 2024 - frontierspartnerships.org
De novo thrombotic microangiopathy (TMA) is a rare and challenging condition in kidney
transplant recipients, with limited research on its incidence and impact on graft survival. This …
transplant recipients, with limited research on its incidence and impact on graft survival. This …