Natural polymeric scaffolds in bone regeneration

M Filippi, G Born, M Chaaban… - … in bioengineering and …, 2020 - frontiersin.org
Despite considerable advances in microsurgical techniques over the past decades, bone
tissue remains a challenging arena to obtain a satisfying functional and structural restoration …

Scaffold design for bone regeneration

L Polo-Corrales, M Latorre-Esteves… - … of nanoscience and …, 2014 - ingentaconnect.com
The use of bone grafts is the standard to treat skeletal fractures, or to replace and regenerate
lost bone, as demonstrated by the large number of bone graft procedures performed …

Stimuli‐responsive supramolecular hydrogels and their applications in regenerative medicine

J Hoque, N Sangaj, S Varghese - Macromolecular bioscience, 2019 - Wiley Online Library
Supramolecular hydrogels are a class of self‐assembled network structures formed via non‐
covalent interactions of the hydrogelators. These hydrogels capable of responding to …

Multicomponent hydrogels for the formation of vascularized bone-like constructs in vitro

B Derkus, BO Okesola, DW Barrett, M D'Este… - Acta biomaterialia, 2020 - Elsevier
The native extracellular matrix (ECM) is a complex gel-like system with a broad range of
structural features and biomolecular signals. Hydrogel platforms that can recapitulate the …

Self-assembled peptide amphiphile nanofibers and PEG composite hydrogels as tunable ECM mimetic microenvironment

M Goktas, G Cinar, I Orujalipoor, S Ide… - …, 2015 - ACS Publications
Natural extracellular matrix (ECM) consists of complex signals interacting with each other to
organize cellular behavior and responses. This sophisticated microenvironment can be …

Bimolecular based heparin and self-assembling hydrogel for tissue engineering applications

T Fernández-Muiños, L Recha-Sancho… - Acta biomaterialia, 2015 - Elsevier
One major goal of tissue engineering is to develop new biomaterials that are similar
structurally and functionally to the extracellular matrix (ECM) to mimic natural cell …

Self-assembling peptide-based delivery of therapeutics for myocardial infarction

KM French, I Somasuntharam, ME Davis - Advanced drug delivery reviews, 2016 - Elsevier
Cardiovascular disease, including myocardial infarction, is the number one cause of death.
Current treatments are palliative and slow the progression toward heart failure, but to not …

[PDF][PDF] Bone graft substitutes for bone defect regeneration. A collective review

M Kheirallah, H Almeshaly - Int J Dentistry Oral Sci, 2016 - researchgate.net
Objective: The purpose of this review article is to illustrate the current state of development of
bone graft substitutes that could be used for bone defect regeneration, as well as to analyze …

Erlotinib promotes ligand-induced EGFR degradation in 3D but not 2D cultures of pancreatic ductal adenocarcinoma cells

N Betriu, A Andreeva, CE Semino - Cancers, 2021 - mdpi.com
Simple Summary The EGFR is a tyrosine kinase receptor that responds to different stresses
such as UV irradiation, hypoxia and drug treatment by internalizing into endosomal …

Controlling osteogenic stem cell differentiation via soft bioinspired hydrogels

AK Jha, WM Jackson, KE Healy - PloS one, 2014 - journals.plos.org
Osteogenic differentiation of human mesenchymal stem cells (hMSCs) is guided by various
physical and biochemical factors. Among these factors, modulus (ie, rigidiy) of the ECM has …