Puberty is the period of transition from childhood to adulthood characterized by the
attainment of adult height and body composition, accrual of bone strength and the …

The syndrome of impaired GH secretion (GH deficiency) in childhood and adolescence had
been identified at the end of the 19th century. Its non-acquired variant (naGHD) is, at …

Pediatric endocrinologists often evaluate and treat youth with delayed puberty.
Stereotypically, these patients are 14-year-old young men who present due to lack of …

Methods: The published studies and articles of the international literature were used
regarding the approach to adolescent girls with hypogonadism. Results: The aim of therapy …

Puberty, which in humans is considered to include both gonadarche and adrenarche, is the
period of becoming capable of reproducing sexually and is recognized by maturation of the …

Background: Isolated Hypogonadotropic Hypogonadism (IHH) is a clinical syndrome that
results from gonadal failure due to abnormal pituitary gonadotropin levels, in the presence of …

This review focuses on primary amenorrhea and primary/premature ovarian insufficiency
due to hypergonadotropic hypogonadism. Following a thoughtful, thorough evaluation, a …

The term 'differences of sex development'(DSD) refers to a group of congenital conditions
that are associated with atypical development of chromosomal, gonadal, and/or anatomical …

Delayed puberty is one of the most common presentations seen by pediatric
endocrinologists. 1 It is defined as the absence of clinical signs of activation of the …

Puberty consists of two components: gonadarche and adrenarche. Gonadarche reflects
reactivation of the hypothalamic gonadotropin releasing hormone (GnRH) pulse generator …