Wilms tumour is the most common renal malignancy of childhood. The disease is curable in
the majority of cases, albeit at considerable cost in terms of late treatment-related effects in …

In Europe, almost 1000 children are diagnosed with a malignant renal tumour each year.
The vast majority of cases are nephroblastoma, also known as Wilms' tumour (WT). Most …

Kidney tumours are among the most common solid tumours in children, comprising distinct
subtypes differing in many aspects, including cell-of-origin, genetics, and pathology. Pre …

We performed genome-wide sequencing and analyzed mRNA and miRNA expression, DNA
copy number, and DNA methylation in 117 Wilms tumors, followed by targeted sequencing …

We report the most common single-nucleotide substitution/deletion mutations in favorable
histology Wilms tumors (FHWTs) to occur within SIX1/2 (7% of 534 tumors) and microRNA …

Background Wilms tumour is the most common childhood renal cancer and is genetically
heterogeneous. While several Wilms tumour predisposition genes have been identified …

Renal malignancies are among the most prevalent pediatric cancers. The most common is
favorable histology Wilms tumor (FHWT), which has 5‐year overall survival exceeding 90 …

Wilms tumor is the most common pediatric renal tumor, accounting for approximately 7% of
all childhood cancers. Imaging plays an important role in the detection, staging, post-therapy …

DICER1 is an endoribonuclease central to the generation of microRNAs (miRNAs) and short
interfering RNAs (siRNAs). Germline mutations in DICER1 have been associated with a …

Wilms' tumor, or nephroblastoma, is the most common pediatric renal cancer. The tumors
morphologically resemble embryonic kidneys with a disrupted architecture and are …