Gradual degradation of fucoidan from Fucus vesiculosus and its effect on structure, antioxidant and antiproliferative activities

E Lahrsen, I Liewert, S Alban - Carbohydrate polymers, 2018 - Elsevier
The fucose-containing sulfated polysaccharides (syn. fucoidans) from brown algae exhibit a
wide range of bioactivities and are therefore considered promising candidates for health …

Phytoagents for cancer management: regulation of nucleic acid oxidation, ROS, and related mechanisms

WL Lee, JY Huang, LF Shyur - Oxidative medicine and cellular …, 2013 - Wiley Online Library
Accumulation of oxidized nucleic acids causes genomic instability leading to senescence,
apoptosis, and tumorigenesis. Phytoagents are known to reduce the risk of cancer …

Initial evaluation of six different brown algae species as source for crude bioactive fucoidans

KS Bittkau, S Neupane, S Alban - Algal Research, 2020 - Elsevier
The fucose-containing sulfated polysaccharides (syn. fucoidans) from brown seaweeds
exhibit multiple biological activities. The aim of the present study was to evaluate the …

[HTML][HTML] Structural features, kinetics and SAR study of radical scavenging and antioxidant activities of phenolic and anilinic compounds

HM Ali, A Abo-Shady, HA Sharaf Eldeen… - Chemistry Central …, 2013 - Springer
Background Phenolic compounds are widely distributed in plant kingdom and constitute one
of the most important classes of natural and synthetic antioxidants. In the present study fifty …

Quercetin and EGCG exhibit chemopreventive effects in cholangiocarcinoma cells via suppression of JAK/STAT signaling pathway

L Senggunprai, V Kukongviriyapan… - Phytotherapy …, 2014 - Wiley Online Library
Quercetin and epigallocatechin‐3‐gallate (EGCG) are dietary phytochemicals with
antiinflammatory and antitumor effects. In the present study, we examined the effects of …

[PDF][PDF] Structure-activity relationships of oleanane-and ursane-type triterpenoids

H Sun, WS Fang, WZ Wang, C Hu - Botanical Studies, 2006 - ejournal.sinica.edu.tw
The chemistry of oleanane-and ursane-type triterpenoids has been actively explored in
recent years, and their biological and pharmacological activities of these compounds have …

In vitro chemopreventive potential of fucophlorethols from the brown alga Fucus vesiculosus L. by anti-oxidant activity and inhibition of selected cytochrome P450 …

S Parys, S Kehraus, A Krick, KW Glombitza, S Carmeli… - Phytochemistry, 2010 - Elsevier
Within a project focusing on the chemopreventive potential of algal phenols, two
phloroglucinol derivatives, belonging to the class of fucophlorethols, and the known …

Chemical structures of inducers of nicotinamide quinone oxidoreductase 1 (NQO1)

AT Dinkova-Kostova, JW Fahey, P Talalay - Methods in enzymology, 2004 - Elsevier
Publisher Summary This chapter describes the chemical structures of inducers of
nicotinamide quinone oxidoreductase 1 (NQO1). Some studies propose the use of activity of …

Stabilization of p53 is involved in quercetin-induced cell cycle arrest and apoptosis in HepG2 cells

S Tanigawa, M Fujii, DX Hou - Bioscience, biotechnology, and …, 2008 - academic.oup.com
There is evidence for defects in the mechanisms that allow the activation of p53 in many of
the cancers that retain wild-type p53. Reactivation of p53 has been suggested to be an …

Dietary and medicinal antimutagens and anticarcinogens: molecular mechanisms and chemopreventive potential—highlights of a symposium

YJ Surh, LR Ferguson - Mutation Research/Fundamental and Molecular …, 2003 - Elsevier
Antimutagens and anticarcinogens are common amongst many traditional herbal remedies
and dietary therapies. With increased understanding of the mechanistic basis of cancer …