Sperm deoxyribonucleic acid (DNA) damage has recently emerged as one of the most
controversial topics in male reproductive medicine. While level I evidence indicates that …

Based on the inconsistent literature published thus far involving infertile patients, whether
intracytoplasmic sperm injection (ICSI) allows overcoming total fertilization failure due to …

Intracytoplasmic sperm injection (ICSI) using surgically retrieved spermatozoa outside the
classic context of azoospermia has been increasingly used to overcome infertility. The …

If you and your spouse have been trying to conceive for a year and neither of you has been
successful, there is a possibility that you are one of the 50–80 million people throughout the …

Background and Objectives: Sperm DNA fragmentation refers to any break in one or both of
the strands of DNA in the head of a sperm. The most widely used methodologies for …

Several studies show reductions in some seminal parameters in aged men and describe
them as a consequence of many age-dependent changes in male organisms. This study …

Maternal effect senescence, a decline in offspring viability with maternal age, has been
documented across diverse animals, but its mechanisms remain largely unknown. Here, we …

Mutations accumulate in the genome of every cell of the body throughout life, causing
cancer and other genetic diseases 1–4. Almost all of these mosaic mutations begin as …

Exposure to endocrine disruptors such as bisphenols, can lead to and be the explanation for
idiopathic infertility. In our study, we assessed the effect of exposure to bisphenol S (BPS) …

Simple Summary Oxidatively stressed sperm can fertilise oocytes and, hence, transfer its
damaged genome to a progeny. Sperm cannot repair its own genome, therefore the oocyte's …