A novel series of melatonin receptor ligands, characterized by a N-(substituted-anilinoethyl)
amido scaffold, along with preliminary structure–activity relationships (SARs), is presented …

A novel series of 2-[(2, 3-dihydro-1 H-indol-1-yl) methyl] melatonin analogues has been
prepared to probe the steric and electronic properties of the binding pocket of the MT2 …

A structure for the self-condensation product of 2-(1H-indol-2-yl) ethyl tosylate2a, previously
proposed as 6, 7, 14, 15-tetrahydro-15aH-azocino [1, 2-a: 6, 5-b] diindole3a, was revised …

Two novel series of melatonin-derived compounds have been synthesized and
pharmacologically evaluated at the MT1 and MT2 subtypes of melatonin receptors …

A series of naphthalenic analogues of melatonin were prepared and evaluated as melatonin
receptor MT2 selective ligands. Activity and MT2 selectivity can be modulated with suitable …

We report herein an efficient synthesis of 2-substituted furo [3, 2-b] pyridines and their
biological evaluation as melatonin receptors ligands. The proposed eight-step sequence …

Publisher Summary This chapter is a sequel to nine already published surveys in “Advances
in Heterocyclic Chemistry”. It includes a list of monographs and reviews published during the …

Abstract Racemic N‐(8‐methoxy‐10, 11‐dihydro‐5H‐dibenzo [a, d] cyclohepten‐10‐
ylmethyl) acetamide (compound 5) was previously identified as a novel selective MT2 …

A synthesis and pharmacological evaluation of new melatonin receptor ligands obtained by
2-substitution of melatonin with (indol-1-yl) methyl,(isoindolin-2-yl) methyl, and …

A series of 7-azaindolic ligands bearing a methoxy group and a N-acetyl chain as
melatoninergic pharmacophores were synthesized and their binding affinities towards MT1 …