[HTML][HTML] Biomarkers in colorectal cancer: current research and future prospects

OO Ogunwobi, F Mahmood, A Akingboye - International journal of …, 2020 - mdpi.com
Colorectal cancer (CRC) is a leading cause of death worldwide, despite progress made in
detection and management through surgery, chemotherapy, radiotherapy, and …

[HTML][HTML] Radiomics and machine learning applications in rectal cancer: current update and future perspectives

A Stanzione, F Verde, V Romeo… - World Journal of …, 2021 - ncbi.nlm.nih.gov
The high incidence of rectal cancer in both sexes makes it one of the most common tumors,
with significant morbidity and mortality rates. To define the best treatment option and …

[HTML][HTML] Early diagnosis of liver metastases from colorectal cancer through CT radiomics and formal methods: a pilot study

A Rocca, MC Brunese, A Santone, P Avella… - Journal of Clinical …, 2021 - mdpi.com
Background: Liver metastases are a leading cause of cancer-associated deaths in patients
affected by colorectal cancer (CRC). The multidisciplinary strategy to treat CRC is more …

Trends in the characteristics, treatment, and outcomes of rectal adenocarcinoma in the US from 2004 to 2019: A National Cancer Database Analysis

SH Emile, N Horesh, MR Freund, Z Garoufalia… - JAMA …, 2023 - jamanetwork.com
Importance Rectal cancer management has significantly evolved over the last 2 decades.
Objective This study aimed to evaluate trends in the characteristics, treatment, and outcomes …

T cell antigen recognition and discrimination by electrochemiluminescence imaging

Y Yan, P Zhou, L Ding, W Hu, W Chen… - Angewandte …, 2023 - Wiley Online Library
Adoptive T lymphocyte (T cell) transfer and tumour‐specific peptide vaccines are innovative
cancer therapies. An accurate assessment of the specific reactivity of T cell receptors (TCRs) …

[HTML][HTML] Identification of hub genes and potential molecular mechanisms related to radiotherapy sensitivity in rectal cancer based on multiple datasets

P Zhao, H Zhen, H Zhao, Y Huang, B Cao - Journal of Translational …, 2023 - Springer
Background Radiotherapy resistance is the main cause of low tumor regression for locally
advanced rectum adenocarcinoma (READ). The biomarkers correlated to radiotherapy …

The prognostic potential of CDX2 in colorectal cancer: Harmonizing biology and clinical practice

J Badia-Ramentol, F Gimeno-Valiente… - Cancer Treatment …, 2023 - Elsevier
Adjuvant chemotherapy following surgical intervention remains the primary treatment option
for patients with localized colorectal cancer (CRC). However, a significant proportion of …

Detection of cancer cells and tumor margins during colorectal cancer surgery by intraoperative flow cytometry

VK Georvasili, GS Markopoulos, A Batistatou… - International Journal of …, 2022 - Elsevier
Abstract Background Flow Cytometry is an analytical technique for the precise quantification
of cellular phenotype. Intraoperative Flow Cytometry (iFC) utilizes flow cytometry for DNA …

Neoadjuvant chemotherapy is noninferior to chemoradiotherapy for early-onset locally advanced rectal cancer in the FOWARC trial

J Cai, K Lin, T Luo, J Weng, H Liu, Z Yuan… - British Journal of …, 2024 - nature.com
Background The early-onset rectal cancer with rapidly increasing incidence is considered to
have distinct clinicopathological and molecular profiles with high-risk features. This leads to …

[HTML][HTML] The evolution of rectal cancer treatment: the journey to total neoadjuvant therapy and organ preservation

A Affleck IV, MA Koprowski… - Annals of …, 2022 - ncbi.nlm.nih.gov
There has been a staggering increase in the incidence of rectal cancer, drawing our
attention to early detection and optimization of its medical and surgical treatment. With this …