The protein corona spontaneously develops and evolves on the surface of nanoscale
materials when they are exposed to biological environments, altering their physiochemical …

Cancer nanomedicines were initially envisioned as magic bullets, travelling through the
circulation to target tumours while sparing healthy tissues the toxicity of classic …

An inconvenient hurdle in the practice of nanomedicine is the protein corona, a spontaneous
collection of biomolecular species by nanoparticles in living systems. The protein corona is …

Nanoparticles (NPs) in biological fluids form a layer of biomolecules known as the protein
corona. The protein corona has been shown to determine the biological identity and in vivo …

Nanoparticle-based therapeutics and diagnostics are commonly referred to as
nanomedicine and may significantly impact the future of healthcare. However, the clinical …

Nanoparticles from natural and anthropogenic sources are abundant in the environment,
thus human exposure to nanoparticles is inevitable. Due to this constant exposure, it is …

Effective delivery of therapeutic and diagnostic nanoparticles is dependent on their ability to
accumulate in diseased tissues. However, most nanoparticles end up in liver macrophages …

Lymph node follicles capture and retain antigens to induce germinal centers and long-lived
humoral immunity. However, control over antigen retention has been limited. Here we …

Various functional nanomaterials have been fabricated as diagnostic and therapeutic
nanomedicines; however, the nanoparticles closely interact with proteins when immersed in …

Blood proteins adsorb onto the surface of nanoparticles after intravenous injection to form a
protein corona. The underlying organization and binding function of these adsorbed proteins …