Live-dead assay on unlabeled cells using phase imaging with computational specificity
Existing approaches to evaluate cell viability involve cell staining with chemical reagents.
However, the step of exogenous staining makes these methods undesirable for rapid …
However, the step of exogenous staining makes these methods undesirable for rapid …
Machine learning assisted classification of cell lines and cell states on quantitative phase images
AV Belashov, AA Zhikhoreva, TN Belyaeva, AV Salova… - Cells, 2021 - mdpi.com
In this report, we present implementation and validation of machine-learning classifiers for
distinguishing between cell types (HeLa, A549, 3T3 cell lines) and states (live, necrosis …
distinguishing between cell types (HeLa, A549, 3T3 cell lines) and states (live, necrosis …
Investigating fibroblast cells under “safe” and “injurious” blue‐light exposure by holographic microscopy
The exposure to visible light has been shown to exert various biological effects, such as
erythema and retinal degeneration. However, the phototoxicity mechanisms in living cells …
erythema and retinal degeneration. However, the phototoxicity mechanisms in living cells …
In vitro cytotoxicity evaluation of cadmium by label‐free holographic microscopy
Among all environmental pollutants, the toxic heavy metal cadmium is considered as a
human carcinogen. Cadmium may induce cell death by apoptosis in various cell types …
human carcinogen. Cadmium may induce cell death by apoptosis in various cell types …
Label‐free high temporal resolution assessment of cell proliferation using digital holographic microscopy
B Janicke, A Kårsnäs, P Egelberg, K Alm - Cytometry Part A, 2017 - Wiley Online Library
Cell proliferation assays are widely applied in biological sciences to understand the effect of
drugs over time. However, current methods often assess cell population growth indirectly …
drugs over time. However, current methods often assess cell population growth indirectly …
Novel optical approaches for label-free quantification of nano-cytotoxic effects
S Mues, J Antunovic, S Ketelhut… - Biophysics, Biology …, 2016 - spiedigitallibrary.org
Commonly used cytotoxicity assays to determine the formation of reactive oxygen species,
cell viability or cell death are often affected by applied nanomaterials, which lead to false …
cell viability or cell death are often affected by applied nanomaterials, which lead to false …
Digital holographic microscopy as multimodal read out for in vitro nanomaterial cytotoxicity testing
Digital holographic microscopy as multimodal read out for in vitro nanomaterial cytotoxicity
testing Page 1 Digital holographic microscopy as multimodal read out for in vitro …
testing Page 1 Digital holographic microscopy as multimodal read out for in vitro …
Optical analysis of nanomaterial-cell interactions: Flow cytometry and digital holographic microscopy
S Mues, J Antunovic, R Ossig… - Optical Methods for …, 2015 - spiedigitallibrary.org
The in vitro cytotoxicity assessment of engineered nanoparticles commonly involves the
measurement of different endpoints like the formation of reactive oxygen species, cell …
measurement of different endpoints like the formation of reactive oxygen species, cell …
Digital holographic microscopy overcomes the limitations of in vitro nanomaterial cytotoxicity testing
The cytotoxic potential of nanomaterials is commonly evaluated by different cellular
endpoints as reactive oxygen species formation, cell viability or cell death. Usually these …
endpoints as reactive oxygen species formation, cell viability or cell death. Usually these …
Testing of bioactive-nanovesicles on hepatotoxicity of atypical antipsychotics via digital holography
Atypical antipsychotic drugs induce hepatic toxicity. Thus, it is of importance to eliminate the
side effects of these drugs. Herein we describe the preparation of nanoemulsions with a …
side effects of these drugs. Herein we describe the preparation of nanoemulsions with a …