The aim of this study is to perform a systematic review of the costing methodological
approaches adopted by published cost-of-illness (COI) studies. A systematic review was …

Hemodynamic overload in the heart can trigger maladaptive hypertrophy of cardiomyocytes.
A key signaling event in this process is nuclear acetylation by histone deacetylases and …

Objectives. This study sought to investigate the clinical characteristics of patients with
chronic heart failure and an increased ventilatory response to exercise and to examine the …

Objectives: The purpose of this study was to create an automated surveillance tool for
reporting the incidence, prevalence and processes of care for patients with heart failure …

▪ Abstract This review discusses the rapidly progressing field of cardiomyocyte signal
transduction and the regulation of the hypertrophic response. When stimulated by a wide …

Patients with rheumatoid arthritis (RA) have an excess burden of cardiovascular (CV)
disease (CVD). CV risk scores for the general population may not accurately predict CV risk …

BACKGROUND: Despite the fact that 80% of patients with heart failure are aged more than
65 years, recognition of cognitive impairment by physicians in this population has received …

Background—Contemporary survival in unselected patients with heart failure and the
population impact of newer therapies have not been widely studied. Therefore, we have …

In human disease and experimental animal models, depressed Ca 2+ handling in failing
cardiomyocytes is widely attributed to impaired sarcoplasmic reticulum (SR) function. In …

Little is known about the burden of illness associated with advanced congestive heart failure
(CHF). Understanding the needs of this population requires further information about …