The emergence of immune checkpoint inhibitors (ICIs) as a pillar of cancer treatment has
emphasized the immune system's integral role in tumor control and progression through …

Immunotherapy consisted mainly of immune checkpoint inhibitors (ICIs) has led to
significantly improved antitumor response. However, such response has been observed …

Background Small‐cell lung cancer (SCLC) is characterized by rapid proliferation and early
dissemination. The objective of this study was to examine the demographic trends and …

Background When concurrent chemoradiotherapy (CCRT) is administered for limited-stage
small cell lung cancer (LS-SCLC), the early incorporation of thoracic radiotherapy (TRT) is …

The standard treatment for limited-stage small cell lung cancer (SCLC) is concurrent
chemoradiation, with a small subset of patients that could potentially benefit from surgery …

Optimal management of cancer patients relies heavily on late-phase oncology randomized
controlled trials. A comprehensive understanding of the key considerations in designing and …

Objective Patients with small cell lung cancer (SCLC) have a high risk of developing brain
metastases (BM). Prophylactic cranial irradiation (PCI) is a standard therapy for limited-stage …

Simple Summary The selection of radiation dose/fractionation schemes for limited-stage
small cell lung cancer (LS-SCLC) is highly controversial. It mainly involves the impact of total …

The Oncology Grand Rounds series is designed to place original reports published in the
Journal into clinical context. A case presentation is followed by a description of diagnostic …

Objective: The purpose of this research was to develop a model for brain metastasis (BM) in
limited-stage small cell lung cancer (LS-SCLC) patients and to help in the early identification …