Abstract Treatment of hypotonic hyponatremia often challenges clinicians on many counts.
Despite similar serum sodium concentrations, clinical manifestations can range from mild to …

Disruption of normal gastrointestinal function as a result of infection, hereditary or acquired
diseases, or complications of surgical procedures uncovers its important role in acid-base …

We examined the cell-specific subcellular expression patterns for sodium-and potassium-
coupled chloride (NaK2Cl) cotransporter 1 (NKCC1), Na+ bicarbonate cotransporter …

Sodium bicarbonate is the mainstay treatment of the metabolic acidosis of chronic kidney
disease but associated concerns center on administering sodium to patients with …

BACKGROUND: Patients with ileostomies are well known to be susceptible to extracellular
fluid volume depletion as a result of fluid and solute losses that are greater than intake …

Background Hydrogen cross-feeding microbes form a functionally important subset of the
human colonic microbiota. The three major hydrogenotrophic functional groups of the colon …

Maintenance of a constant hydrogen ion concen-tration (pH) is critical for health. Among the
reasons a constant pH is important is that enzymatic reactions have a “pH optimum” that is …

La acidosis metabólica es el trastorno ácido base más complejo de estudiar, originada
como consecuencia de la pérdida de bicarbonato; la ganancia de hidrogeniones o la falta …

Concomitant severe metabolic alkalosis, hypernatremia, and kidney failure pose a
therapeutic challenge. Hemodialysis to correct azotemia and abnormal electrolytes results in …

In this chapter, the pathogenesis, diagnosis, clinical manifestations, and treatment of various
types of acid–base disorders due to disruption of normal gastrointestinal function are …