[HTML][HTML] Evaluating sheep hemoglobins with MD simulations as an animal model for sickle cell disease
Sickle cell disease (SCD) affects millions worldwide, yet there are few therapeutic options.
To develop effective treatments, preclinical models that recapitulate human physiology and …
To develop effective treatments, preclinical models that recapitulate human physiology and …
The Influence of Voxelotor on Cerebral Blood Flow and Oxygen Extraction in Pediatric Sickle Cell Disease
RO Brothers, KB Turrentine, M Akbar, S Triplett, H Zhao… - Blood, 2024 - Elsevier
Voxelotor is an inhibitor of sickle hemoglobin polymerization that is used to treat sickle cell
disease. While voxelotor has been shown to improve anemia, the clinical benefit on the …
disease. While voxelotor has been shown to improve anemia, the clinical benefit on the …