3D bioprinted liver tissue and disease models: Current advances and future perspectives

L Sun, Y Wang, S Zhang, H Yang, Y Mao - Biomaterials Advances, 2023 - Elsevier
Abstract Three-dimensional (3D) bioprinting is a promising technology for fabricating
complex tissue constructs with biomimetic biological functions and stable mechanical …

Recent Progress in Fabrication of Electrospun Nanofiber Membranes for Developing Physiological In Vitro Organ/Tissue Models

D Kim, J Youn, J Lee, H Kim… - Macromolecular …, 2023 - Wiley Online Library
Nanofiber membranes (NFMs), which have an extracellular matrix‐mimicking structure and
unique physical properties, have garnered great attention as biomimetic materials for …

Large-scale high-throughput 3D culture, imaging, and analysis of cell spheroids using microchip-enhanced light-sheet microscopy

T Zhu, J Nie, T Yu, D Zhu, Y Huang, Z Chen… - Biomedical Optics …, 2023 - opg.optica.org
Light sheet microscopy combined with a microchip is an emerging tool in biomedical
research that notably improves efficiency. However, microchip-enhanced light-sheet …

[HTML][HTML] 3D bioprinting of an endothelialized liver lobule-like construct as a tumor-scale drug screening platform

Z Fan, X Wei, K Chen, L Wang, M Xu - Micromachines, 2023 - mdpi.com
3D cell culture models replicating the complexity of cell–cell interactions and biomimetic
extracellular matrix (ECM) are novel approaches for studying liver cancer, including in vitro …

Double Digital Assay for Single Extracellular Vesicle and Single Molecule Detection

DE Reynolds, M Pan, J Yang, G Galanis… - Advanced …, 2023 - Wiley Online Library
Extracellular vesicles (EVs) have emerged as a promising source of biomarkers for disease
diagnosis. However, current diagnostic methods for EVs present formidable challenges …

[HTML][HTML] Microstructured soft devices for the growth and analysis of populations of homogenous multicellular tumor spheroids

O Tartagni, A Borók, E Mensà, A Bonyár… - Cellular and Molecular …, 2023 - Springer
Multicellular tumor spheroids are rapidly emerging as an improved in vitro model with
respect to more traditional 2D culturing. Microwell culturing is a simple and accessible …

[HTML][HTML] Constructing liver-like tissue in situ based on plant-derived cellulose scaffolds alleviating acute liver injury

J Hu, S He, D Zhang, Z Wang, S Zhao, X Shi, W Li… - Materials & Design, 2024 - Elsevier
Despite the promise of tissue engineering for treating acute liver injury (ALI), functional
vascular system construction is still not fully achieved in liver tissue engineering …

Combinatorial drug screening based on massive 3d tumor cultures using micropatterned array chips

W Fu, M Sun, J Zhang, T Xuanyuan, X Liu… - Analytical …, 2023 - ACS Publications
The establishment and application of a generalizable three-dimensional (3D) tumor device
for high-throughput screening plays an important role in drug discovery and cancer …

基于脱细胞方法制备3D 植物肝组织工程支架及表征

胡婧婧, 何松霖, 张大旭, 赵烁, 史潇楠, 李伟龙… - 中国组织工程研究, 2024 - cjter.com
基于脱细胞方法制备3D 植物肝组织工程支架及表征 Page 1 Chinese Journal of Tissue
Engineering Research|Vol 28|No.29|October 2024|4645 中国组织工程研究 Chinese Journal of …

[PDF][PDF] Scalable production of uniform and mature organoids in a 3D geometrically-engineered permeable membrane

DS Kim, D Kim, H Lim, J Youn, TE Park - 2023 - scholar.archive.org
The application of organoids has been limited by the lack of methods for producing uniformly
mature organoids at scale. This study introduces an organoid culture platform, called …