Modeling ventilator-induced lung injury and neutrophil infiltration to infer injury interdependence

CL Mattson, BJ Smith - Annals of Biomedical Engineering, 2023 - Springer
Acute respiratory distress syndrome (ARDS) and ventilator-induced lung injury (VILI) are
heterogeneous conditions. The spatiotemporal evolution of these heterogeneities is …

[HTML][HTML] Evaluation of lung aeration and respiratory system mechanics in obese dogs ventilated with tidal volumes based on ideal vs. current body weight

J Araos, L Lacitignola, V de Monte, M Stabile… - Frontiers in Veterinary …, 2021 - frontiersin.org
We describe the respiratory mechanics and lung aeration in anesthetized obese dogs
ventilated with tidal volumes (VT) based on ideal (VTi) vs. current (VTc) body weight. Six …

Spatiotemporal distribution of cellular injury and leukocytes during the progression of ventilator-induced lung injury

CL Mattson, K Okamura, PS Hume… - American Journal of …, 2022 - journals.physiology.org
Supportive mechanical ventilation is a necessary lifesaving treatment for acute respiratory
distress syndrome (ARDS). This intervention often leads to injury exacerbation by ventilator …

[HTML][HTML] Perfusion imaging heterogeneity during NO inhalation distinguishes pulmonary arterial hypertension (PAH) from healthy subjects and has potential as an …

T Winkler, P Kohli, VJ Kelly, EG Kehl, AS Witkin… - Respiratory …, 2022 - Springer
Background Without aggressive treatment, pulmonary arterial hypertension (PAH) has a 5-
year mortality of approximately 40%. A patient's response to vasodilators at diagnosis …

Effects of Positive End-expiratory Pressure on Pulmonary Perfusion Distribution and Intrapulmonary Shunt during One-lung Ventilation in Pigs: A Randomized …

J Wittenstein, M Scharffenberg, J Fröhlich… - …, 2024 - pubs.asahq.org
Background During one-lung ventilation (OLV), positive end-expiratory pressure (PEEP) can
improve lung aeration but might overdistend lung units and increase intrapulmonary shunt …

Pulmonary Pathophysiology and Lung Mechanics in Anesthesiology

JL Sparling, MFV Melo - Cohen's Comprehensive Thoracic Anesthesia, 2022 - Elsevier
The practice of thoracic anesthesia involves not only patients with impaired pulmonary
function, it also necessitates dynamic changes in ventilation with resulting impact on …

Spatiotemporal Evolution of Cellular Injury and Leukocyte Infiltration During Ventilator-Induced Lung Injury: Quantitative Analyses and Computational Modelling

C Mattson - 2023 - search.proquest.com
Severe injury and illness may lead to acute respiratory distress syndrome (ARDS): a high
mortality acute respiratory failure that has an incidence of up to 80 cases per 100,000 …

Radiology of the Thorax

JH Campos, A Sharma - Cohen's Comprehensive Thoracic Anesthesia, 2022 - Elsevier
Radiologic images play an important role during evaluation of patients undergoing thoracic
surgery. Radiologic studies must be reviewed, including a posterior-anterior chest …

[图书][B] Parameters Governing Airway Pressure Homogeneity During Low Frequency Jet Ventilation

JD Pertile - 2019 - search.proquest.com
Low frequency jet ventilation (LFJV) is a widely used form of ventilation that currently has no
defined safe pressures or flow rates because the methodology for safe and effective …