Molecular mechanisms of dietary restriction promoting health and longevity
CL Green, DW Lamming, L Fontana - Nature Reviews Molecular Cell …, 2022 - nature.com
Dietary restriction with adequate nutrition is the gold standard for delaying ageing and
extending healthspan and lifespan in diverse species, including rodents and non-human …
extending healthspan and lifespan in diverse species, including rodents and non-human …
Mitochondrial dysfunction in aging
Y Guo, T Guan, K Shafiq, Q Yu, X Jiao, D Na… - Ageing Research …, 2023 - Elsevier
Aging is a complex process that features a functional decline in many organelles. Although
mitochondrial dysfunction is suggested as one of the determining factors of aging, the role of …
mitochondrial dysfunction is suggested as one of the determining factors of aging, the role of …
Effect of long-term caloric restriction on DNA methylation measures of biological aging in healthy adults from the CALERIE trial
The geroscience hypothesis proposes that therapy to slow or reverse molecular changes
that occur with aging can delay or prevent multiple chronic diseases and extend healthy …
that occur with aging can delay or prevent multiple chronic diseases and extend healthy …
Caloric restriction in humans reveals immunometabolic regulators of health span
The extension of life span driven by 40% caloric restriction (CR) in rodents causes trade-offs
in growth, reproduction, and immune defense that make it difficult to identify therapeutically …
in growth, reproduction, and immune defense that make it difficult to identify therapeutically …
Effects of intermittent fasting on health, aging, and disease
R De Cabo, MP Mattson - New England Journal of Medicine, 2019 - Mass Medical Soc
Effects of Intermittent Fasting on Health and Aging Evidence is accumulating that eating in a
6-hour period and fasting for 18 hours can trigger a metabolic switch from glucose-based to …
6-hour period and fasting for 18 hours can trigger a metabolic switch from glucose-based to …
Importance of circadian timing for aging and longevity
VA Acosta-Rodríguez, F Rijo-Ferreira, CB Green… - Nature …, 2021 - nature.com
Dietary restriction (DR) decreases body weight, improves health, and extends lifespan. DR
can be achieved by controlling how much and/or when food is provided, as well as by …
can be achieved by controlling how much and/or when food is provided, as well as by …
Antiaging diets: Separating fact from fiction
BACKGROUND Reduced caloric intake without malnutrition is the oldest known life span–
extending intervention. Laboratory studies throughout the 20th century established and …
extending intervention. Laboratory studies throughout the 20th century established and …
A time to fast
Nutrient composition and caloric intake have traditionally been used to devise optimized
diets for various phases of life. Adjustment of meal size and frequency have emerged as …
diets for various phases of life. Adjustment of meal size and frequency have emerged as …
Impact of intermittent fasting on health and disease processes
Humans in modern societies typically consume food at least three times daily, while
laboratory animals are fed ad libitum. Overconsumption of food with such eating patterns …
laboratory animals are fed ad libitum. Overconsumption of food with such eating patterns …
[HTML][HTML] The effects of intermittent fasting on brain and cognitive function
The importance of diet and the gut-brain axis for brain health and cognitive function is
increasingly acknowledged. Dietary interventions are tested for their potential to prevent …
increasingly acknowledged. Dietary interventions are tested for their potential to prevent …