Nanomedicine embraces cancer radio-immunotherapy: mechanism, design, recent advances, and clinical translation
Cancer radio-immunotherapy, integrating external/internal radiation therapy with immuno-
oncology treatments, emerges in the current management of cancer. A growing number of …
oncology treatments, emerges in the current management of cancer. A growing number of …
Immune checkpoint pathways in immunotherapy for head and neck squamous cell carcinoma
Z Mei, J Huang, B Qiao, AK Lam - International journal of oral science, 2020 - nature.com
With the understanding of the complex interaction between the tumour microenvironment
and immunotherapy, there is increasing interest in the role of immune regulators in the …
and immunotherapy, there is increasing interest in the role of immune regulators in the …
Immune checkpoint inhibitor combinations: Current efforts and important aspects for success
Immune checkpoint inhibitors (ICI) have emerged as a remarkable treatment option for
diverse cancer types. Currently, ICIs are approved for an expanding array of cancer …
diverse cancer types. Currently, ICIs are approved for an expanding array of cancer …
Combination strategies to augment immune check point inhibitors efficacy-implications for translational research
H Varayathu, V Sarathy, BE Thomas, SS Mufti… - Frontiers in …, 2021 - frontiersin.org
Immune checkpoint inhibitor therapy has revolutionized the field of cancer immunotherapy.
Even though it has shown a durable response in some solid tumors, several patients do not …
Even though it has shown a durable response in some solid tumors, several patients do not …
Lattice or oxygen-guided radiotherapy: what if they converge? Possible future directions in the era of immunotherapy
G Ferini, V Valenti, A Tripoli, SI Illari, L Molino, S Parisi… - Cancers, 2021 - mdpi.com
Simple Summary Oxygen-guided radiotherapy is a new modality for cancer irradiation.
Spatially Fractionated Radiation Therapy allows the treatment of hypoxic tumor areas with …
Spatially Fractionated Radiation Therapy allows the treatment of hypoxic tumor areas with …
Radiotherapy-mediated immunomodulation and anti-tumor abscopal effect combining immune checkpoint blockade
X Zhao, C Shao - Cancers, 2020 - mdpi.com
Simple Summary Combination of radiotherapy and immunotherapy to antagonize tumors is
one of hotspot issues currently. Immunotherapy can effectively alleviate the non-lasting …
one of hotspot issues currently. Immunotherapy can effectively alleviate the non-lasting …
Nanotechnology‐enhanced radiotherapy and the abscopal effect: Current status and challenges of nanomaterial‐based radio‐immunotherapy
Rare but consistent reports of abscopal remission in patients challenge the notion that
radiotherapy (RT) is a local treatment; radiation‐induced cancer cell death can trigger …
radiotherapy (RT) is a local treatment; radiation‐induced cancer cell death can trigger …
Immunotherapy for cervical cancer: are we ready for prime time?
M Turinetto, AA Valsecchi, V Tuninetti, G Scotto… - International Journal of …, 2022 - mdpi.com
The prognosis of invasive cervical cancer (CC) remains poor, with a treatment approach that
has remained the same for several decades. Lately, a better understanding of the …
has remained the same for several decades. Lately, a better understanding of the …
Ionizing radiation effects on the tumor microenvironment
L Portella, S Scala - Seminars in Oncology, 2019 - Elsevier
The broad use of radiotherapy (RT) in the management of solid human tumors is based on
its ability to damage cellular macromolecules, particularly the DNA, effectively inducing …
its ability to damage cellular macromolecules, particularly the DNA, effectively inducing …
Targeting the tumor microenvironment for improving therapeutic effectiveness in cancer immunotherapy: focusing on immune checkpoint inhibitors and combination …
IT Chyuan, CL Chu, PN Hsu - Cancers, 2021 - mdpi.com
Simple Summary Immune checkpoint inhibitors (ICIs) constitute a paradigm shift in cancer
therapy, and it has greatly expanded our knowledge of anticancer immunity and has …
therapy, and it has greatly expanded our knowledge of anticancer immunity and has …