Acinetobacter baumannii is a Gram-negative ESKAPE microorganism that poses a threat to
public health by causing severe and invasive (mostly nosocomial) infections linked with high …

Cefiderocol appears promising, as it can overcome most β-lactam resistance mechanisms
(including β-lactamases, porin mutations, and efflux pumps). Resistance is uncommon …

Infections caused by metallo-β-lactamase (MBL)-producing Enterobacterales and
Pseudomonas are increasingly reported worldwide and are usually associated with high …

Management of patients with infections caused by multidrug-resistant organisms is
challenging and requires a multidisciplinary approach to achieve successful clinical …

Background Cefiderocol is a last resort option for carbapenem-resistant (CR) Gram-negative
bacteria, especially metallo-β-lactamase (MBL)-producing Pseudomonas aeruginosa and …

Antimicrobial drug resistance is one of the major threats to global health. It has made
common infections increasingly difficult or impossible to treat, and leads to higher medical …

The recent increase in outbreaks of pathogenic bacteria and antimicrobial resistance
represent major public health problems. Being the leading cause of death in humans, the …

Stenotrophomonas maltophilia is an urgent global threat due to its increasing incidence and
intrinsic antibiotic resistance. Antibiotic development has focused on carbapenem-resistant …

Antibiotic resistance has emerged as an imminent pandemic. Rapid diagnostic assays
distinguish bacterial infections from other diseases and aid antimicrobial stewardship …

Currently, the efficacy of antibiotics is severely affected by the emergence of the
antimicrobial resistance phenomenon, leading to increased morbidity and mortality …