Pirfenidone: a promising drug in ocular therapeutics

AC Bisen, S Agrawal, R Rayiti, SN Sanap… - Chemistry & …, 2024 - Wiley Online Library
Pirfenidone, initially indicated for lung fibrosis, has gone beyond its original purpose, and
shown promise in eye care. This detailed review tracks its evolution from lung treatment to …

Recent updates on ocular disease management with ophthalmic ointments

AC Bisen, A Dubey, S Agrawal, A Biswas… - Therapeutic …, 2024 - Taylor & Francis
Ophthalmic diseases can result in permanent vision loss and blindness. Convenient topical
and systemic treatments are preferred to address these sight-threatening conditions …

Ocular bioanalysis of moxifloxacin and ketorolac tromethamine in rabbit lacrimal matrix using liquid chromatography–tandem mass spectrometry

AC Bisen, RS Bhatta - Bioanalysis, 2024 - Taylor & Francis
Aim: The fixed-dose combination of moxifloxacin (MOXI) and ketorolac tromethamine (KTR)
is widely used for the treatment of bacterial keratitis. Thus, a new LC–MS/MS method was …

Concurrent determination of anti-microbial and anti-inflammatory drugs in lachrymal fluid and tissue by LC-MS/MS: A potential treatment for microbial keratitis and its …

A Mishra, AD Choudhury, A Biswas, V Singh… - … of Pharmaceutical and …, 2024 - Elsevier
Unforeseen surfacing of microbial keratitis (MKT) over the years has led to a requisite for
promising treatment strategy involving combination of antifungal and antibacterial agents …

Pharmaceutical Emulsions: A Viable Approach for Ocular Drug Delivery

AC Bisen, S Srivastava, A Mishra… - Journal of Ocular …, 2024 - liebertpub.com
Ocular disorders can lead to serious sight impairment and irreversible blindness. Generally
simple topical and systemic treatments are recommended for treating these vision …

Polymers and their engineered analogues for ocular drug delivery: Enhancing therapeutic precision

A Biswas, S Kumar, AD Choudhury, AC Bisen… - …, 2024 - Wiley Online Library
Ocular drug delivery is constrained by anatomical and physiological barriers, necessitating
innovative solutions for effective therapy. Natural polymers like hyaluronic acid, chitosan …

A review on polymers in ocular drug delivery systems

AC Bisen, A Biswas, A Dubey… - MedComm …, 2024 - Wiley Online Library
Amid the escalating prevalence of eye diseases and the intricate nature of the eye as a
crucial target organ for drug delivery, researchers face significant challenges in developing …

Nanomicellar eye drops: a review of recent advances

V Paganini, P Chetoni, M Di Gangi… - Expert Opinion on …, 2024 - Taylor & Francis
Introduction Research on nanotechnology in medicine has also involved the ocular field and
nanomicelles are among the applications developed. This approach is used to increase …

Addressing ocular drug delivery challenges with solid nanofiber variants and supramolecular nanofibrous gel composite

D Sahu, G Rath, G Gupta - Journal of Drug Delivery Science and …, 2024 - Elsevier
Current ocular medication delivery technologies struggle with insufficient drug
bioavailability. Drug nanocarriers with inherent bioadhesion and corneal retention abilities …

Insights into ocular therapeutics: a comprehensive review of anatomy, barriers, diseases and nanoscale formulations for targeted drug delivery

A Chandel, G Kandav - Journal of Drug Delivery Science and Technology, 2024 - Elsevier
Ocular drug delivery systems play a critical role in the treatment of various eye diseases via
ensuring targeted and efficient delivery of therapeutic agent. The complex anatomy and …