[HTML][HTML] Biological drug and drug delivery-mediated immunotherapy

Q Xiao, X Li, Y Li, Z Wu, C Xu, Z Chen, W He - Acta Pharmaceutica Sinica B, 2021 - Elsevier
The initiation and development of major inflammatory diseases, ie, cancer, vascular
inflammation, and some autoimmune diseases are closely linked to the immune system …

Nanoemulgel: a novel nano carrier as a tool for topical drug delivery

MR Donthi, SR Munnangi, KV Krishna, RN Saha… - Pharmaceutics, 2023 - mdpi.com
Nano-emulgel is an emerging drug delivery system intended to enhance the therapeutic
profile of lipophilic drugs. Lipophilic formulations have a variety of limitations, which includes …

Polymer nanomedicines

J Kopeček, J Yang - Advanced drug delivery reviews, 2020 - Elsevier
Polymer nanomedicines (macromolecular therapeutics, polymer-drug conjugates, drug-free
macromolecular therapeutics) are a group of biologically active compounds that are …

Dissolving microneedle patch-assisted transdermal delivery of methotrexate improve the therapeutic efficacy of rheumatoid arthritis

W Zhao, L Zheng, J Yang, Z Ma, X Tao, Q Wang - Drug Delivery, 2023 - Taylor & Francis
Methotrexate (MTX) is a first-line treatment for rheumatoid arthritis (RA), but its clinical use is
greatly limited by the adverse effects and poor patient compliance caused by traditional oral …

[HTML][HTML] Microneedles-based drug delivery strategies: A breakthrough approach for the management of pain

S Priya, G Singhvi - Biomedicine & Pharmacotherapy, 2022 - Elsevier
Pain is a personalized event or body alarm system that can limit a patient's activities and
lead to negative repercussions. The commercially available conventional treatment …

Topical delivery of curcumin-loaded transfersomes gel ameliorated rheumatoid arthritis by inhibiting NF-κβ pathway

E Sana, M Zeeshan, QU Ain, AU Khan, I Hussain… - …, 2021 - Taylor & Francis
Aim: To fabricate and evaluate curcumin-loaded transfersomes (Cur-TF) for the targeted
delivery and enhanced therapeutic efficacy of curcumin for the treatment of rheumatoid …

Programmable polymeric microneedles for combined chemotherapy and antioxidative treatment of rheumatoid arthritis

C Wu, J Cheng, W Li, L Yang, H Dong… - ACS Applied Materials …, 2021 - ACS Publications
Rheumatoid arthritis (RA) is a chronic inflammatory joint disease. Antioxidative treatment
combined with chemotherapy holds great promise for RA treatment, and the ability to …

Hyaluronic acid-coated proglycosomes for topical delivery of tofacitinib in rheumatoid arthritis condition: Formulation design, in vitro, ex vivo characterization, and in …

S Gorantla, ER Puppala, VGM Naidu, RN Saha… - International Journal of …, 2023 - Elsevier
Tofacitinib (TF) is a selective oral jakanib approved by the USFDA for the treatment of
rheumatoid arthritis (RA). To overcome the adverse effects of orally administered TF, topical …

Luliconazole loaded lyotropic liquid crystalline nanoparticles for topical delivery: QbD driven optimization, in-vitro characterization and dermatokinetic assessment

A Mahmood, VK Rapalli, T Waghule, S Gorantla… - Chemistry and physics …, 2021 - Elsevier
Fungal infections are an important cause of morbidity and pose a serious health concern
especially in immunocompromised patients. Luliconazole (LUL) is a topical imidazole …

Emerging insights of peptide-based nanotherapeutics for effective management of rheumatoid arthritis

V Pathade, S Nene, S Ratnam, DK Khatri… - Life Sciences, 2023 - Elsevier
Rheumatoid arthritis (RA) is a chronic, prevalent, immune-mediated, inflammatory, joint
disorder affecting millions of people worldwide. Despite current treatment options, many …