Intravitreal injection of anti-vascular endothelial growth factor (VEGF) agents is increasingly
used for the treatment of a wide variety of retinal diseases, including age-related macular …

The efficacy of drugs administered by traditional routes is limited by numerous biological
barriers that preclude reaching the intended site of action. Further, full body systemic …

Purpose: To review evidence and provide updated guidelines on intravitreal (IVT) injection
technique and monitoring. Methods: A review of the published literature on IVT injection from …

The number of eye diseases treated with intravitreal injections is increasing. Obviously, an
injection of fluid into the eye results in an increase of intraocular pressure (IOP), the main …

Purpose.: To quantify levels of subvisible particles and protein aggregates in repackaged
bevacizumab obtained from compounding pharmacies, as well as in samples of …

Purpose To describe the incidence, features, management, and risk factors of post-
intravitreal anti-VEGF endophthalmitis (PIAE) in patients undergoing treatment for exudative …

Angiogenesis is a clue process for tissue development and function, both in normal and
pathological conditions. This process is regulated by multiple molecular systems. One of the …

Central retinal artery occlusion (CRAO) has been known as a clinical entity since 1859,
when von Graefe [1] first described CRAO due to embolism. After that, Schweigger [2] in …

Purpose: To evaluate the occurrence, management, and clinical significance of increases in
intraocular pressure (IOP) in patients with diabetic macular edema treated with …

PURPOSE: We assessed the frequency and predictive factors related to intraocular pressure
(IOP) elevation in neovascular age-related macular degeneration (AMD) patients …