[HTML][HTML] Network pharmacology approach for medicinal plants: review and assessment
Natural products have played a critical role in medicine due to their ability to bind and
modulate cellular targets involved in disease. Medicinal plants hold a variety of bioactive …
modulate cellular targets involved in disease. Medicinal plants hold a variety of bioactive …
A comprehensive application: Molecular docking and network pharmacology for the prediction of bioactive constituents and elucidation of mechanisms of action in …
X Jiao, X Jin, Y Ma, Y Yang, J Li, L Liang, R Liu… - … Biology and Chemistry, 2021 - Elsevier
Traditional Chinese medicine (TCM) has been used for more than 2000 years in China.
TCM has received wide attention recently due to its unique charm. At the same time, its main …
TCM has received wide attention recently due to its unique charm. At the same time, its main …
Nose to brain drug delivery-a promising strategy for active components from herbal medicine for treating cerebral ischemia reperfusion
Y Long, Q Yang, Y Xiang, Y Zhang, J Wan, S Liu… - Pharmacological …, 2020 - Elsevier
Cerebral ischemia reperfusion injury (CIRI), one of the major causes of death from stroke in
the world, not only causes tremendous damage to human health, but also brings heavy …
the world, not only causes tremendous damage to human health, but also brings heavy …
[HTML][HTML] Protective effects and target network analysis of ginsenoside Rg1 in cerebral ischemia and reperfusion injury: a comprehensive overview of experimental …
W Xie, P Zhou, Y Sun, X Meng, Z Dai, G Sun, X Sun - Cells, 2018 - mdpi.com
Cerebral ischemia-reperfusion is a complicated pathological process. The injury and
cascade reactions caused by cerebral ischemia and reperfusion are characterized by high …
cascade reactions caused by cerebral ischemia and reperfusion are characterized by high …
Microwave assisted extraction, characterization of a polysaccharide from Salvia miltiorrhiza Bunge and its antioxidant effects via ferroptosis-mediated activation of the …
H Meng, J Wu, L Shen, G Chen, L Jin, M Yan… - International Journal of …, 2022 - Elsevier
A microwave-assisted extraction procedure for the crude Salvia miltiorrhiza polysaccharides
(SMPs) obtained from Salvia miltiorrhiza Bunge was optimized. Four independent variables …
(SMPs) obtained from Salvia miltiorrhiza Bunge was optimized. Four independent variables …
Melatonin protected cardiac microvascular endothelial cells against oxidative stress injury via suppression of IP3R-[Ca2+]c/VDAC-[Ca2+]m axis by activation of …
H Zhu, Q Jin, Y Li, Q Ma, J Wang, D Li, H Zhou… - Cell Stress and …, 2018 - Springer
The cardiac microvascular reperfusion injury is characterized by the microvascular
endothelial cells (CMECs) oxidative damage which is responsible for the progression of …
endothelial cells (CMECs) oxidative damage which is responsible for the progression of …
Effects and mechanisms of compound Chinese medicine and major ingredients on microcirculatory dysfunction and organ injury induced by ischemia/reperfusion
JY Han, Q Li, ZZ Ma, JY Fan - Pharmacology & therapeutics, 2017 - Elsevier
Microcirculation dysfunction and organ injury after ischemia and reperfusion (I/R) result from
a complex pathologic process consisting of multiple links, with metabolism impairment in the …
a complex pathologic process consisting of multiple links, with metabolism impairment in the …
[HTML][HTML] Mechanisms of dexmedetomidine in neuropathic pain
Y Zhao, J He, N Yu, C Jia, S Wang - Frontiers in neuroscience, 2020 - frontiersin.org
Dexmedetomidin is a new-generation, highly selective α2 adrenergic receptor agonist with a
large number of advantages, including its sedative and analgesic properties, its ability to …
large number of advantages, including its sedative and analgesic properties, its ability to …
[HTML][HTML] Tissue engineering strategies for peripheral nerve regeneration
Y Li, Z Ma, Y Ren, D Lu, T Li, W Li, J Wang… - Frontiers in …, 2021 - frontiersin.org
A peripheral nerve injury (PNI) has severe and profound effects on the life of a patient. The
therapeutic approach remains one of the most challenging clinical problems. In recent years …
therapeutic approach remains one of the most challenging clinical problems. In recent years …
Focusing on claudin-5: a promising candidate in the regulation of BBB to treat ischemic stroke
J Lv, W Hu, Z Yang, T Li, S Jiang, Z Ma, F Chen… - Progress in …, 2018 - Elsevier
Claudin-5 is a tight junction (TJ) protein in the blood-brain barrier (BBB) that has recently
attracted increased attention. Numerous studies have demonstrated that claudin-5 regulates …
attracted increased attention. Numerous studies have demonstrated that claudin-5 regulates …