The liver plays a vital role in metabolism, synthesis, and detoxification, but it is susceptible to
damage from various factors such as viral infections, drug reactions, excessive alcohol …

Background As a canonical iron-dependent form of regulated cell death (RCD), ferroptosis
plays a crucial role in chemical-induced liver injuries. Previous studies have demonstrated …

Abstract Ethnopharmacological relevance Clinopodium chinense (Benth.) O. Kuntze (C.
chinense) is a Chinese herbal medicine used in treating gynecological hemorrhagic …

Oxidative stress is one of the most important factors in changing bone homeostasis. Redox
homeostasis plays a key role in the osteogenic differentiation of bone mesenchymal stem …

Ethnopharmacological relevance Panax japonicus (T. Nees) CA Mey.(PJ) has been used as
a tonic traditional Chinese medicine (TCM) for years. Based on its meridian tropism in liver …

Hepatic ischemia/reperfusion (I/R) injury is an unavoidable complication of liver
hepatectomy, transplantation, and systemic shock. Pectolinarigenin (Pec) is a flavonoid with …

Acetaminophen (APAP) is the most used non-prescription drug throughout the world. At
therapeutic doses, APAP has potent analgesic and antipyretic effects. The efficacy and …

Amyotrophic lateral sclerosis (ALS) is considered a fatal progressive degeneration of motor
neurons (MN) caused by oxidative stress and mitochondrial dysfunction. There are currently …

Abstract Ethnopharmacological relevance Fufang Zhenzhu TiaoZhi (FTZ), a Chinese
medicinal decoction, has continuously been used to treat metabolic syndrome …

Abstract Ethnopharmacological relevance The Chinese medicine Daji (the aerial part of
Cirsium japonicum DC.) and its charred product (Cirsii Japonici Herba Carbonisata) have …