Adult sequelae of intrauterine growth restriction

MG Ross, MH Beall - Seminars in perinatology, 2008 - Elsevier
Fetal intrauterine growth restriction has been associated with adult disease in both human
epidemiologic studies and in animal models. In some cases, intrauterine deprivation …

What happens when children with fetal alcohol spectrum disorders become adults?

EM Moore, EP Riley - Current developmental disorders reports, 2015 - Springer
The range of structural abnormalities and functional deficits caused by prenatal alcohol
exposure (PAE) are referred to as fetal alcohol spectrum disorders (FASDs). The disabilities …

[HTML][HTML] Prenatal alcohol-induced sex differences in immune, metabolic and neurobehavioral outcomes in adult rats

S Bake, MR Pinson, S Pandey, JP Chambers… - Brain, Behavior, and …, 2021 - Elsevier
Prenatal alcohol exposure (PAE) can result in neurobehavioral anomalies, that may be
exacerbated by co-occurring metabolic and immune system deficits. To test the hypothesis …

Fetal alcohol spectrum disorder predisposes to metabolic abnormalities in adulthood

O Weeks, GD Bossé, IM Oderberg… - The Journal of …, 2020 - Am Soc Clin Investig
Prenatal alcohol exposure (PAE) affects at least 10% of newborns globally and leads to the
development of fetal alcohol spectrum disorders (FASDs). Despite its high incidence, there …

Molecular mechanisms governing offspring metabolic programming in rodent models of in utero stress

ER Christoforou, AN Sferruzzi-Perri - Cellular and Molecular Life Sciences, 2020 - Springer
The results of different human epidemiological datasets provided the impetus to introduce
the now commonly accepted theory coined as 'developmental programming', whereby the …

Early life factors and type 2 diabetes mellitus

X Jiang, H Ma, Y Wang, Y Liu - Journal of diabetes research, 2013 - Wiley Online Library
Type 2 diabetes mellitus (T2DM) is a multifactorial disease, and its aetiology involves a
complex interplay between genetic, epigenetic, and environmental factors. In recent years …

Fetal programming is deeply related to maternal selenium status and oxidative balance; experimental offspring health repercussions

ML Ojeda, F Nogales, I Romero-Herrera, O Carreras - Nutrients, 2021 - mdpi.com
Nutrients consumed by mothers during pregnancy and lactation can exert permanent effects
upon infant developing tissues, which could represent an important risk factor for diseases …

Prenatal ethanol exposure programs an increased susceptibility of non-alcoholic fatty liver disease in female adult offspring rats

L Shen, Z Liu, J Gong, L Zhang, L Wang… - Toxicology and applied …, 2014 - Elsevier
Prenatal ethanol exposure (PEE) induces dyslipidemia and hyperglycemia in fetus and adult
offspring. However, whether PEE increases the susceptibility to non-alcoholic fatty liver …

Epigenetics of the developing and aging brain: Mechanisms that regulate onset and outcomes of brain reorganization

ER Bacon, RD Brinton - Neuroscience & Biobehavioral Reviews, 2021 - Elsevier
Brain development is a life-long process that encompasses several critical periods of
transition, during which significant cognitive changes occur. Embryonic development …

Periconceptional alcohol consumption causes fetal growth restriction and increases glycogen accumulation in the late gestation rat placenta

EM Gårdebjer, JSM Cuffe, M Pantaleon, ME Wlodek… - Placenta, 2014 - Elsevier
Introduction Alcohol consumption is a common social practice among women of
childbearing age. With 50% of pregnancies being unplanned, many embryos are exposed to …