Adult sequelae of intrauterine growth restriction
MG Ross, MH Beall - Seminars in perinatology, 2008 - Elsevier
Fetal intrauterine growth restriction has been associated with adult disease in both human
epidemiologic studies and in animal models. In some cases, intrauterine deprivation …
epidemiologic studies and in animal models. In some cases, intrauterine deprivation …
What happens when children with fetal alcohol spectrum disorders become adults?
The range of structural abnormalities and functional deficits caused by prenatal alcohol
exposure (PAE) are referred to as fetal alcohol spectrum disorders (FASDs). The disabilities …
exposure (PAE) are referred to as fetal alcohol spectrum disorders (FASDs). The disabilities …
[HTML][HTML] Prenatal alcohol-induced sex differences in immune, metabolic and neurobehavioral outcomes in adult rats
Prenatal alcohol exposure (PAE) can result in neurobehavioral anomalies, that may be
exacerbated by co-occurring metabolic and immune system deficits. To test the hypothesis …
exacerbated by co-occurring metabolic and immune system deficits. To test the hypothesis …
Fetal alcohol spectrum disorder predisposes to metabolic abnormalities in adulthood
O Weeks, GD Bossé, IM Oderberg… - The Journal of …, 2020 - Am Soc Clin Investig
Prenatal alcohol exposure (PAE) affects at least 10% of newborns globally and leads to the
development of fetal alcohol spectrum disorders (FASDs). Despite its high incidence, there …
development of fetal alcohol spectrum disorders (FASDs). Despite its high incidence, there …
Molecular mechanisms governing offspring metabolic programming in rodent models of in utero stress
ER Christoforou, AN Sferruzzi-Perri - Cellular and Molecular Life Sciences, 2020 - Springer
The results of different human epidemiological datasets provided the impetus to introduce
the now commonly accepted theory coined as 'developmental programming', whereby the …
the now commonly accepted theory coined as 'developmental programming', whereby the …
Early life factors and type 2 diabetes mellitus
X Jiang, H Ma, Y Wang, Y Liu - Journal of diabetes research, 2013 - Wiley Online Library
Type 2 diabetes mellitus (T2DM) is a multifactorial disease, and its aetiology involves a
complex interplay between genetic, epigenetic, and environmental factors. In recent years …
complex interplay between genetic, epigenetic, and environmental factors. In recent years …
Fetal programming is deeply related to maternal selenium status and oxidative balance; experimental offspring health repercussions
Nutrients consumed by mothers during pregnancy and lactation can exert permanent effects
upon infant developing tissues, which could represent an important risk factor for diseases …
upon infant developing tissues, which could represent an important risk factor for diseases …
Prenatal ethanol exposure programs an increased susceptibility of non-alcoholic fatty liver disease in female adult offspring rats
L Shen, Z Liu, J Gong, L Zhang, L Wang… - Toxicology and applied …, 2014 - Elsevier
Prenatal ethanol exposure (PEE) induces dyslipidemia and hyperglycemia in fetus and adult
offspring. However, whether PEE increases the susceptibility to non-alcoholic fatty liver …
offspring. However, whether PEE increases the susceptibility to non-alcoholic fatty liver …
Epigenetics of the developing and aging brain: Mechanisms that regulate onset and outcomes of brain reorganization
ER Bacon, RD Brinton - Neuroscience & Biobehavioral Reviews, 2021 - Elsevier
Brain development is a life-long process that encompasses several critical periods of
transition, during which significant cognitive changes occur. Embryonic development …
transition, during which significant cognitive changes occur. Embryonic development …
Periconceptional alcohol consumption causes fetal growth restriction and increases glycogen accumulation in the late gestation rat placenta
Introduction Alcohol consumption is a common social practice among women of
childbearing age. With 50% of pregnancies being unplanned, many embryos are exposed to …
childbearing age. With 50% of pregnancies being unplanned, many embryos are exposed to …