Opiate abuse and HIV-1 have been described as interrelated epidemics, and even in the
advent of combined anti-retroviral therapy, the additional abuse of opiates appears to result …

Illegal addictive drugs can lead to functional or structural impairment of the central nervous
system. This review provides an overview of the structural imaging findings on CT, MR …

Milroy CM & Parai JL (2011) Histopathology 59, 579–593 The histopathology of drugs of
abuse The use of drugs for recreational purposes is widespread. The drugs used can be …

The current opioid epidemic necessitates a better understanding of human addiction
neurobiology to develop efficacious treatment approaches. Here, we perform genome-wide …

The observation of increased hyperphosphorylated tau levels correlating with microglial
activation in opiate abusers has been interpreted as predisposition to accelerated Alzheimer …

Importance Opioid addiction affects approximately 2.4 million Americans. Nearly 1 million
individuals, including a growing subset of 21 000 minors, abuse heroin. Its annual cost …

Drug abuse is a major problem worldwide. The incidence of drugrelated deaths attributed
to opiate abuse is increasing annually. Apart from routine examination, little is known of the …

Opioid use disorder (OUD) has gained increasing publicity and interest during recent years,
with many countries describing problems of epidemic proportions with regard to opioid use …

It has been previously suggested that morphine can regulate the expression and function of
some proteins of the cytoskeleton. In the present study, we used real-time quantitative …

The central nervous system is one of the primary targets for the detrimental effects of drugs
of abuse. Diagnostic imaging, especially MRI, plays an important role in the detection of …