Non-fatal opioid overdose (NFOO) is a significant cause of opioid-related morbidity in the
United States. As the number of NFOOs continues to grow, it is important to understand the …

The central nervous system is one of the primary targets for the detrimental effects of drugs
of abuse. Diagnostic imaging, especially MRI, plays an important role in the detection of …

Despite two decades of research, certain aspects of HIV-related central nervous system
(CNS) disease remain poorly understood. HIV targets microglia and macrophages within the …

Objective To investigate frequent findings in cases of fatal opioid intoxication in whole-body
post-mortem computed tomography (PMCT). Methods PMCT of 55 cases in which heroin …

[Frontiers in Bioscience 13, 1294-1307, January 1, 2008] 1294 The effects of illicit drugs on
the HIV infected brain Iain Crawf Page 1 [Frontiers in Bioscience 13, 1294-1307, January 1 …

Heroin is a highly addictive drug that causes axonal damage. Here, manganese-enhanced
magnetic resonance imaging (MEMRI) was used to dynamically monitor axonal transport at …

While these toxic leukoencephalopathies may present with acute, severe alteration of
mental state necessitating hospital admission, they may also present with a more indolent …

Objective Toxic leukoencephalopathy is a rare but critical neurological disorder in heroin
abusers. Our aim is to compare the clinical manifestations, brain MRIs and prognoses of …

Abstract Human immunodeficiency virus (HIV)1 infection can cause characteristic neural
defects such as progressive motor dysfunction, striatal pathology and gliosis. Recent …

Background Adult neurogenesis has been shown to occur throughout life and different brain
pathologies were demonstrated to be associated with altered neurogenesis. Here, an impact …