Simulation and artificial intelligence in rhinoplasty: a systematic review

AS Eldaly, FR Avila, RA Torres-Guzman, K Maita… - Aesthetic Plastic …, 2022 - Springer
Background Rhinoplasty is one of the most popular cosmetic procedures. The complexity of
the nasal structure and the substantial aesthetic and functional impact of the operation make …

Patient specific CFD models of nasal airflow: overview of methods and challenges

SK Kim, Y Na, JI Kim, SK Chung - Journal of biomechanics, 2013 - Elsevier
Respiratory physiology and pathology are strongly dependent on the airflow inside the nasal
cavity. However, the nasal anatomy, which is characterized by complex airway channels and …

[HTML][HTML] Development of intranasal implantable devices for schizophrenia treatment

E Utomo, J Domínguez-Robles… - International journal of …, 2022 - Elsevier
In this work the preparation and characterisation of intranasal implants for the delivery of
risperidone (RIS) is described. The aim of this work is to develop better therapies to treat …

In situ-gelling starch nanoparticle (SNP)/O-carboxymethyl chitosan (CMCh) nanoparticle network hydrogels for the intranasal delivery of an antipsychotic peptide

MJ Majcher, A Babar, A Lofts, A Leung, X Li… - Journal of controlled …, 2021 - Elsevier
Existing oral or injectable antipsychotic drug delivery strategies typically demonstrate low
bioavailability to targeted brain regions, incentivizing the development of alternative delivery …

Normative ranges of nasal airflow variables in healthy adults

AAT Borojeni, GJM Garcia, MG Moghaddam… - International journal of …, 2020 - Springer
Purpose Virtual surgery planning based on computational fluid dynamics (CFD) simulations
of nasal airflow has the potential to improve surgical outcomes for patients with nasal airway …

Effects of surface smoothness on inertial particle deposition in human nasal models

JD Schroeter, GJM Garcia, JS Kimbell - Journal of aerosol science, 2011 - Elsevier
Computational fluid dynamics (CFD) predictions of inertial particle deposition have not
compared well with data from nasal replicas due to effects of surface texture and the …

The importance of pre-formulation studies and of 3D-printed nasal casts in the success of a pharmaceutical product intended for nose-to-brain delivery

L Deruyver, C Rigaut, P Lambert, B Haut… - Advanced drug delivery …, 2021 - Elsevier
This review aims to cement three hot topics in drug delivery:(a) the pre-formulation of new
products intended for nose-to-brain delivery;(b) the development of nasal casts for studying …

Personalized medicine in nasal delivery: the use of patient-specific administration parameters to improve nasal drug targeting using 3D-printed nasal replica casts

ZN Warnken, HDC Smyth, DA Davis… - Molecular …, 2018 - ACS Publications
Effective targeting of nasal spray deposition could improve local, systemic, and CNS drug
delivery; however, this has proven to be difficult due to the anatomical features of the nasal …

In vitro deposition measurement of inhaled micrometer-sized particles in extrathoracic airways of children and adolescents during nose breathing

L Golshahi, ML Noga, RB Thompson… - Journal of Aerosol …, 2011 - Elsevier
An in vitro study was conducted with the goal of developing empirical correlations to predict
the deposition of particles with an aerodynamic diameter of 0.5–5.3 μm in nasal airways of …

In vitro assessment of an idealized nose for nasal spray testing: Comparison with regional deposition in realistic nasal replicas

JZ Chen, M Kiaee, AR Martin, WH Finlay - International journal of …, 2020 - Elsevier
An idealized nasal replica that mimics average regional deposition of nasal spray pump
droplets in human nasal airways would potentially be useful in expediting the development …