Near-infrared spectroscopic applications in pharmaceutical particle technology

M Razuc, A Grafia, L Gallo… - Drug Development …, 2019 - Taylor & Francis
Near-infrared spectroscopy (NIRS) is nowadays an established analytical technique in the
pharmaceutical industry. The aim of this review is to present the progress of NIRS in …

Chemometrics-assisted solid-state characterization of pharmaceutically relevant materials. Polymorphic substances

NL Calvo, RM Maggio, TS Kaufman - Journal of pharmaceutical and …, 2018 - Elsevier
Current regulations command to properly characterize pharmaceutically relevant solid
systems. Chemometrics comprise a range of valuable tools, suitable to process large …

Miniaturized X-ray powder diffraction assay (MixRay) for quantitative kinetic analysis of solvent-mediated phase transformations in pharmaceutics

W Kirchmeyer, O Grassmann, N Wyttenbach… - … of pharmaceutical and …, 2016 - Elsevier
Many pharmaceutical compounds exhibit polymorphism, which may result in solvent-
mediated phase transformations. Since the polymorphic form has an essential influence on …

Two solid forms of tauroursodeoxycholic acid and the effects of milling and storage temperature on solid-state transformations

K Xu, S Zheng, Y Zhai, L Guo, P Tang, J Yan… - International Journal of …, 2015 - Elsevier
Two phase-pure solid forms of tauroursodeoxycholic acid (TUDCA) were prepared and
characterized by thermal analysis, vibrational spectroscopy, X-ray diffraction, solid-state …

Mapping the polymorphic forms of fexofenadine in pharmaceutical tablets using near infrared chemical imaging

AM Brondi, LA Terra, GP Sabin… - Journal of Near …, 2014 - journals.sagepub.com
This study presents a comparison of partial least squares (PLS) and multivariate curve
resolution (MCR-ALS) in the quantification of polymorphic forms I and II of fexofenadine. HCl …

[PDF][PDF] Using near infrared spectroscopy to quickly analyze different nitrogens during the shortcut biological removal of nitrogen from a polluted river

J Huang, M Li, H Zhang, Y Zhang, J Liu, W Sun… - Polish Journal of …, 2019 - pjoes.com
During shortcut biological nitrogen removal in a polluted river, total nitrogen, ammonia
nitrogen and nitrite nitrogen were quantified by near infrared spectroscopy and the synergy …

Study of drug-excipient interactions regarding solubility enhancement in diluted aqueous media and solid state transformations

W Saal - 2017 - edoc.unibas.ch
Nearly all marketed dosage forms comprise pharmaceutical excipients that have multiple
functions, for example, improvement of wettability, solubilization, or absorption …