Cytokine storm—definition, causes, and implications

D Jarczak, A Nierhaus - International journal of molecular sciences, 2022 - mdpi.com
The human innate and adaptive immune systems consist of effector cells producing
cytokines (interleukins, interferons, chemokines, and numerous other mediators). Usually, a …

Brain injury after cardiac arrest

GD Perkins, CW Callaway, K Haywood, RW Neumar… - The Lancet, 2021 - thelancet.com
As more people are surviving cardiac arrest, focus needs to shift towards improving
neurological outcomes and quality of life in survivors. Brain injury after resuscitation, a …

European resuscitation council and European society of intensive care medicine guidelines 2021: post-resuscitation care

JP Nolan, C Sandroni, BW Böttiger, A Cariou… - Resuscitation, 2021 - Elsevier
Abstract The European Resuscitation Council (ERC) and the European Society of Intensive
Care Medicine (ESICM) have collaborated to produce these post-resuscitation care …

Mitochondrial transplantation therapy for ischemia reperfusion injury: a systematic review of animal and human studies

K Hayashida, R Takegawa, M Shoaib, T Aoki… - Journal of Translational …, 2021 - Springer
Background Mitochondria are essential organelles that provide energy for cellular functions,
participate in cellular signaling and growth, and facilitate cell death. Based on their …

The role of inflammatory cytokines in cardiac arrest

C Jou, R Shah, A Figueroa… - Journal of intensive care …, 2020 - journals.sagepub.com
Introduction: Post-cardiac arrest syndrome (PCAS) is characterized by systemic
ischemia/reperfusion injury, anoxic brain injury, and post-arrest myocardial dysfunction …

Cytokine hemoadsorption with CytoSorb® in post-cardiac arrest syndrome, a pilot randomized controlled trial

C Monard, N Bianchi, E Poli, M Altarelli… - Critical Care, 2023 - Springer
Background Hemoadsorption (HA) might mitigate the systemic inflammatory response
associated with post-cardiac arrest syndrome (PCAS) and improve outcomes. Here, we …

Prehospital high-dose methylprednisolone in resuscitated out-of-hospital cardiac arrest patients (STEROHCA): a randomized clinical trial

LER Obling, RP Beske, MAS Meyer, J Grand… - Intensive Care …, 2023 - Springer
Purpose Patients who are successfully resuscitated following out-of-hospital cardiac arrest
(OHCA) are still at a high risk of neurological damage and death. Inflammation and brain …

Inflammatory response after out‐of‐hospital cardiac arrest—Impact on outcome and organ failure development

AMJ Seppä, MB Skrifvars… - Acta Anaesthesiologica …, 2023 - Wiley Online Library
Background Post‐cardiac arrest syndrome that occurs in out‐of‐hospital cardiac arrest
(OHCA) patients is characterized by inflammatory response. We conducted a scoping review …

AA147 ameliorates post-cardiac arrest cerebral ischemia/reperfusion injury through the co-regulation of the ATF6 and Nrf2 signaling pathways

Z Yuan, L Lu, Y Lian, Y Zhao, T Tang, S Xu… - Frontiers in …, 2022 - frontiersin.org
Ischemia/reperfusion caused by cardiac arrest (CA) disturbs endoplasmic reticulum (ER)
homeostasis and redox balance in neurons. AA147, originally developed as a …

[HTML][HTML] Disseminated intravascular coagulation in cardiac arrest and resuscitation

S Gando, T Wada - Journal of Thrombosis and Haemostasis, 2019 - Elsevier
The aims of this review are to demonstrate that the changes in coagulation and fibrinolysis
observed in cardiac arrest and resuscitation can be recognized as disseminated …