RISUG® as a male contraceptive: journey from bench to bedside

B Khilwani, A Badar, AS Ansari, NK Lohiya - Basic and Clinical Andrology, 2020 - Springer
Even after decades of research men still lack reliable and reversible contraceptive methods
comparable to female methods of contraception. Traditional methods of male contraception …

[HTML][HTML] Promising results in development of male contraception

Z Dominiak, H Huras, P Kręcisz, W Krzeszowski… - Bioorganic & Medicinal …, 2021 - Elsevier
Nowadays, conscious planning of the family is very important for many people. The
possibility of using protective measures against unplanned pregnancy is a great comfort …

Safety & efficacy of an intravasal, one-time injectable & non-hormonal male contraceptive (RISUG): A clinical experience

RS Sharma, AK Mathur, R Singh, HC Das… - Indian Journal of …, 2019 - journals.lww.com
Methods: One hundred and thirty nine young males each having at least two children and
living with wife were given 120 μl of RISUG as bilateral vas intraluminal injection. After the …

Contraception with RISUG® and functional reversal through DMSO and NaHCO3 in male rabbits

AS Ansari, A Badar, K Balasubramanian… - Asian journal of …, 2017 - journals.lww.com
The study aimed to evaluate reversal of short-and long-term vas occlusion with reversible
inhibition of sperm under guidance (RISUG) using dimethyl sulfoxide (DMSO) and sodium …

Male contraception

D Handelsman, G Waites - Andrology for the Clinician, 2015 - Springer
Kim ED, Winkel E, Orejuela F, Lipshultz LI (1998) Pathological epididymal obstruction
unrelated to vasectomy: results with microsurgical reconstruction. J Urol 160: 2078–2080 …

Preparing for sperm‐targeted contraception: College students' perceptions and intentions related to non‐hormonal intravas injectable gel

KA Buck, JL Stadick, ML Frazier - Public Health Nursing, 2020 - Wiley Online Library
Objective The objective of the study was to evaluate college students' perceptions and
behavioral intentions related to a new long‐acting reversible contraceptive (LARC) for …

Safety evaluation through genotoxicity and apoptotic markers following RISUG® induced contraception and its reversal in male rabbits

AS Ansari, A Badar, NK Lohiya - Reproductive Toxicology, 2018 - Elsevier
The safety evaluation following vas occlusion with RISUG® and its reversal with DMSO and
NaHCO 3, using genotoxicity tests and apoptotic marker assays, was carried out in rabbits …

Toxicity and mutagenicity evaluation following RISUG contraception reversal in rats

AS Ansari, M Hussain, SR Khan… - International …, 2018 - journals.sagepub.com
Reestablishment of fertility, after a male contraceptive method, is of great concern. In this
context, RISUG (Reversible Inhibition of Sperm Under Guidance) has been evaluated for its …

[HTML][HTML] Reversible inhibition of sperm under guidance as an intratubular and reversible contraception in female rats: An experimental study

AS Ansari, K Sevliya, A Badar… - International journal of …, 2021 - ncbi.nlm.nih.gov
Objective An exploratory study was conducted with a concept of non-invasive, transcervical,
single-intervention and reversible contraception using RISUGⓇ in females. Materials and …

Flexible vesiculovasoscopy using a microoptical system in a human cadaver model: an experimental approach for atraumatic endoscopy of the seminal tract

D Schlager, M Maas, S Hein, F Adams… - Journal of …, 2016 - liebertpub.com
Objectives: The most common pathologies of the seminal tract are persistent
hematospermia, seminal vesicle stones, and seminal duct obstruction. Endoscopic …