Background Increased access to antiretroviral therapy (ART) has resulted in rising levels of
pretreatment human immunodeficiency virus drug resistance (PDR). This is the first …

Despite vaccination and antiviral therapies, immunocompromised individuals are at risk for
prolonged severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, but the …

Abstract Non-suppressible HIV-1 viremia (NSV) is defined as persistent low-level viremia on
antiretroviral therapy (ART) without evidence of ART non-adherence or significant drug …

Background: There are an increasing number of articles focused on the prevalence and
clinical impact of pretreatment HIV drug resistance (PDR) detected by Sanger sequencing …

Despite vaccination and antiviral therapies, immunocompromised individuals are at risk for
prolonged SARS-CoV-2 infection, but the immune defects that predispose to persistent …

Background: Individuals living with human immunodeficiency virus (HIV) who experience
virological failure (VF) after combination antiretroviral therapy (cART) initiation may have …

General consensus suggests that even singleton E138A mutations in HIV reverse
transcriptase at baseline are associated with resistance to rilpivirine (RPV). We detected 11 …

Background Deep sequencing could improve understanding of HIV treatment failure and
viral population dynamics. However, this tool is often inaccessible in low-and middle-income …

Low-frequency mutations associated with drug resistance have been related to virologic
failure in subjects with no history of pre-treatment and recent HIV diagnosis. In total, 78 …

Background Monoclonal antibodies (mAbs) represent a crucial antiviral strategy for severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, but it is unclear whether …