A substantial challenge worldwide is emergent drug resistance in malaria parasites against
approved drugs, such as chloroquine (CQ). To address these unsolved CQ resistance …

Most antimalarials are based on basic N-heterocycles and possess amine functionalities.
Despite this, the role of basic nitrogen (BaN) in antimalarial drug design has not been …

Cinnamic acids are compounds of natural origin that can be found in many different parts of
a wide panoply of plants, where they play the most diverse biological roles, often in a …

The global challenge to the treatment of malaria is mainly the occurrence of resistance of
malaria parasites to conventionally used antimalarials. Artesunate, a semisynthetic …

A silver‐catalyzed protocol for the synthesis of 3‐(1H‐isochromen)‐chromones is described.
The method involves an initial 6‐endo‐dig cyclization of o‐alkynylbenzaldehydes and …

Based on medicinal chemistry tools, new compounds for malaria treatment were designed.
The scaffolds of the drugs used to treat malaria, such as chloroquine, primaquine …

ABSTRACT According to the World Health Organization, malaria remains one of the biggest
public health problems in the world. The development of resistance is a current concern …

A range of antimicrobial peptides (AMP) exhibit activity on malaria parasites, Plasmodium
spp., in their blood or mosquito stages, or both. These peptides include a diverse array of …

Malaria remains a major vector borne disease claiming millions of lives worldwide due to
infections caused by Plasmodium sp. Discovery and development of antimalarial drugs have …

The genus Mycobacterium comprises not only the deadliest of bacterial pathogens,
Mycobacterium tuberculosis, but several other pathogenic species, including M. avium and …