[HTML][HTML] Clinical use of the SelectMDx urinary-biomarker test with or without mpMRI in prostate cancer diagnosis: a prospective, multicenter study in biopsy-naïve men

RJ Hendriks, MMG van der Leest, B Israël… - Prostate cancer and …, 2021 - nature.com
Background Risk stratification in men with suspicion of prostate cancer (PCa) requires
reliable diagnostic tests, not only to identify high-grade PCa, also to minimize the …

[HTML][HTML] Prediction medicine: biomarkers, risk calculators and magnetic resonance imaging as risk stratification tools in prostate cancer diagnosis

DF Osses, MJ Roobol, IG Schoots - International journal of molecular …, 2019 - mdpi.com
This review discusses the most recent evidence for currently available risk stratification tools
in the detection of clinically significant prostate cancer (csPCa), and evaluates diagnostic …

[HTML][HTML] Prostate cancer liquid biopsy biomarkers' clinical utility in diagnosis and prognosis

M Matuszczak, JA Schalken, M Salagierski - Cancers, 2021 - mdpi.com
Simple Summary In prostate cancer, overdiagnosis and overtreatment is a common problem
for clinicians. Accurate diagnosis and prognosis are essential to avoid unnecessary biopsy …

Analysis of magnetic resonance imaging–directed biopsy strategies for changing the paradigm of prostate cancer diagnosis

IG Schoots, AR Padhani, O Rouvière… - European urology …, 2020 - Elsevier
Background The use of a magnetic resonance imaging (MRI)-directed diagnostic pathway in
men at first prostate cancer work-up has been introduced within European prostate cancer …

[HTML][HTML] Androgens, aging, and prostate health

K Welén, JE Damber - Reviews in Endocrine and Metabolic Disorders, 2022 - Springer
Due to late onset hypogonadism (LOH), there is an increased usage of testosterone
replacement therapy (TRT) in the aging male population. Since prostate is a target organ for …

[HTML][HTML] Beyond PSA: the role of prostate health index (phi)

M Ferro, O De Cobelli, G Lucarelli, A Porreca… - International Journal of …, 2020 - mdpi.com
Background: Widespread use of prostate specific antigen (PSA) in screening procedures
allowed early identification of an increasing number of prostate cancers (PCas), mainly …

Smarter screening for prostate cancer

GH Tan, G Nason, K Ajib, DTS Woon… - World Journal of …, 2019 - Springer
Purpose Prostate cancer is the second commonest cancer among men. In the large
European Randomized Study of Screening for Prostate Cancer (ERSPC) trial, prostate …

[HTML][HTML] Genetic landscape of prostate cancer conspicuity on multiparametric magnetic resonance imaging: a systematic review and bioinformatic analysis

JM Norris, BS Simpson, MA Parry, C Allen… - European Urology Open …, 2020 - Elsevier
Context Multiparametric magnetic resonance imaging (mpMRI) detects most, but not all,
clinically significant prostate cancer. The genetic basis of prostate cancer visibility and …

Optimal biopsy approach for detection of clinically significant prostate cancer

S Ippoliti, P Fletcher, L Orecchia… - The British Journal of …, 2022 - academic.oup.com
Prostate cancer (PCa) diagnostic and therapeutic work-up has evolved significantly in the
last decade, with pre-biopsy multiparametric MRI now widely endorsed within international …

Prostate cancer screening—stepping forward with MRI

AR Padhani, IG Schoots - European Radiology, 2023 - Springer
Objective To comprehensively review the literature on the integration of MRI as a diagnostic
tool in prostate cancer screening and offer practical recommendations for optimising its use …