Tumor abnormality-oriented nanomedicine design
Anticancer nanomedicines have been proven effective in mitigating the side effects of
chemotherapeutic drugs. However, challenges remain in augmenting their therapeutic …
chemotherapeutic drugs. However, challenges remain in augmenting their therapeutic …
Chemical design of activatable photoacoustic probes for precise biomedical applications
Y Liu, L Teng, B Yin, H Meng, X Yin, S Huan… - Chemical …, 2022 - ACS Publications
Photoacoustic (PA) imaging technology, a three-dimensional hybrid imaging modality that
integrates the advantage of optical and acoustic imaging, has great application prospects in …
integrates the advantage of optical and acoustic imaging, has great application prospects in …
Detection and analysis of chiral molecules as disease biomarkers
The chirality of small metabolic molecules is important in controlling physiological processes
and indicating the health status of humans. Abnormal enantiomeric ratios of chiral molecules …
and indicating the health status of humans. Abnormal enantiomeric ratios of chiral molecules …
Chemical Biology of H2S Signaling through Persulfidation
MR Filipovic, J Zivanovic, B Alvarez… - Chemical …, 2018 - ACS Publications
Signaling by H2S is proposed to occur via persulfidation, a posttranslational modification of
cysteine residues (RSH) to persulfides (RSSH). Persulfidation provides a framework for …
cysteine residues (RSH) to persulfides (RSSH). Persulfidation provides a framework for …
A review of hydrogen sulfide synthesis, metabolism, and measurement: is modulation of hydrogen sulfide a novel therapeutic for cancer?
X Cao, L Ding, Z Xie, Y Yang, M Whiteman… - Antioxidants & redox …, 2019 - liebertpub.com
Abstract Significance: Hydrogen sulfide (H2S) has been recognized as the third gaseous
transmitter alongside nitric oxide and carbon monoxide. In the past decade, numerous …
transmitter alongside nitric oxide and carbon monoxide. In the past decade, numerous …
[HTML][HTML] Cysteine metabolic circuitries: druggable targets in cancer
VDB Bonifácio, SA Pereira, J Serpa… - British journal of cancer, 2021 - nature.com
To enable survival in adverse conditions, cancer cells undergo global metabolic
adaptations. The amino acid cysteine actively contributes to cancer metabolic remodelling …
adaptations. The amino acid cysteine actively contributes to cancer metabolic remodelling …
[HTML][HTML] Role of oral microbiota in cancer development
TM Karpiński - Microorganisms, 2019 - mdpi.com
Nowadays cancer is the second main cause of death in the world. The most known bacterial
carcinogen is Helicobacter pylori. Pathogens that can have an impact on cancer …
carcinogen is Helicobacter pylori. Pathogens that can have an impact on cancer …
[HTML][HTML] Disturbed homocysteine metabolism is associated with cancer
T Hasan, R Arora, AK Bansal, R Bhattacharya… - … & molecular medicine, 2019 - nature.com
Hyperhomocysteinemia/Homocysteinuria is characterized by an increased level of toxic
homocysteine in the plasma. The plasma concentration of homocysteine is 5–15 μmol/L in …
homocysteine in the plasma. The plasma concentration of homocysteine is 5–15 μmol/L in …
[HTML][HTML] Hydrogen sulfide signaling in mitochondria and disease
B Murphy, R Bhattacharya, P Mukherjee - The FASEB Journal, 2019 - ncbi.nlm.nih.gov
Hydrogen sulfide can signal through 3 distinct mechanisms: 1) reduction and/or direct
binding of metalloprotein heme centers, 2) serving as a potent antioxidant through reactive …
binding of metalloprotein heme centers, 2) serving as a potent antioxidant through reactive …
[HTML][HTML] Oral bacteria and intestinal dysbiosis in colorectal cancer
The human organism coexists with its microbiota in a symbiotic relationship. These
polymicrobial communities are involved in many crucial functions, such as immunity …
polymicrobial communities are involved in many crucial functions, such as immunity …