Abstract miRNAs are small non-coding RNA molecules that modulate the expression of
multiple protein-encoding genes at the post-transcriptional level. They have recently been …

The role of immune response is emerging as a key factor in the complex multistep process of
cancer. Tumor microenvironment contains different types of immune cells, which contribute …

Ablation of a single miRNA gene rarely leads to a discernable developmental phenotype in
mice, in some cases because of compensatory effects by other functionally related miRNAs …

MicroRNA-29b (miR-29b) expression has been shown to be reduced in non-small–cell lung
cancer (NSCLC) tissues. Here, we have identified the oncogene cyclin-dependent protein …

A class of small non-coding RNAs, the microRNAs (miRNAs), have recently attracted great
attention in cancer research since they play a central role in regulation of gene-expression …

MicroRNAs (miRNAs) are small noncoding RNAs that function in post-transcriptional
regulation of gene expression. Dysregulation of miRNAs has been reported in different …

Glutathione depletion and 12-lipoxygenase-dependent metabolism of arachidonic acid are
known to be implicated in neurodegeneration associated with acute ischemic stroke. The …

Background It has been demonstrated that circulating muscle-enriched miR-1 and the
cardiac-specific miR-208 and miR-499 might leak out of the necrotic myocardium and …

Patients diagnosed with osteosarcoma undergo extensive surgical intervention and
chemotherapy resulting in dismal prognosis and compromised quality of life owing to poor …

Cardiovascular disease (CVD), including heart failure, myocardial fibrosis and myocardial
infarction, etc, remains one of the leading causes of mortality worldwide. Evidence shows …