Innovative treatment strategies to accelerate wound healing: trajectory and recent advancements

P Kolimi, S Narala, D Nyavanandi, AAA Youssef… - Cells, 2022 - mdpi.com
Wound healing is highly specialized dynamic multiple phase process for the repair of
damaged/injured tissues through an intricate mechanism. Any failure in the normal wound …

[HTML][HTML] Microenvironmental cue-regulated exosomes as therapeutic strategies for improving chronic wound healing

W Dai, Y Dong, T Han, J Wang, B Gao, H Guo, F Xu… - NPG Asia …, 2022 - nature.com
Exosomes, which are nanoscale vesicles secreted by almost all cell types via paracrine
pathways, play a crucial role in intercellular communication. For nearly a decade, exosomes …

[HTML][HTML] Overview of first-line and second-line pharmacotherapies for osteoarthritis with special focus on intra-articular treatment

A Nowaczyk, D Szwedowski, I Dallo… - International Journal of …, 2022 - mdpi.com
Osteoarthritis (OA) can be defined as the result of pathological processes of various
etiologies leading to damage to the articular structures. Although the mechanism of …

[HTML][HTML] Autologous Platelet and Extracellular Vesicle-Rich Plasma as Therapeutic Fluid: A Review

K Troha, D Vozel, M Arko, A Bedina Zavec… - International journal of …, 2023 - mdpi.com
The preparation of autologous platelet and extracellular vesicle-rich plasma (PVRP) has
been explored in many medical fields with the aim to benefit from its healing potential. In …

[HTML][HTML] Platelet-derived extracellular vesicles ameliorate intervertebral disc degeneration by alleviating mitochondrial dysfunction

Z Dai, C Xia, T Zhao, H Wang, H Tian, O Xu, X Zhu… - Materials Today Bio, 2023 - Elsevier
Mitochondrial dysfunction causes the production of reactive oxygen species (ROS) and
oxidative damage, and oxidative stress and inflammation are considered key factors causing …

Efficacy of Autologous Intrauterine Infusion of Platelet-Rich Plasma in Patients with Unexplained Repeated Implantation Failures in Embryo Transfer: A Systematic …

M Li, Y Kang, Q Wang, L Yan - Journal of Clinical Medicine, 2022 - mdpi.com
(1) Background: Controversial conclusions have been made in previous studies regarding
the influence of autologous platelet-rich plasma (PRP) in the reproductive outcomes of …

[HTML][HTML] Lipoaspirate shows in vitro potential for wound healing

C Ceresa, A Borrone, L Fracchia, M Rinaldi… - Pharmaceutics, 2022 - mdpi.com
Mesenchymal stem cells (MSCs) are a promising therapy in wound healing, although
extensive time and manipulation are necessary for their use. In our previous study on …

Adipose Mesenchymal Stem Cell–Derived Exosomes Promote Keratinocytes And Fibroblasts Embedded in Collagen/Platelet‐Rich Plasma Scaffold And Accelerate …

Y Wang, Y Zhang, T Li, K Shen, KJ Wang… - Advanced …, 2023 - Wiley Online Library
Engineered skin substitutes derived from human skin significantly reduce inflammatory
reactions mediated by foreign/artificial materials and are consequently easier to use for …

[HTML][HTML] Platelet-rich plasma promotes diabetic ulcer repair through inhibition of ferroptosis

L Chen, D Wu, L Zhou, Y Ye - Annals of Translational Medicine, 2022 - ncbi.nlm.nih.gov
Background Ferroptosis, a newly discovered form of cell death, can accumulation activates
lipid peroxidation and excessive oxidative stress in a high glucose environment. These …

Preparation and Characterization of Platelet Lysate (Pl)-Loaded Electrospun Nanofibers for Epidermal Wound Healing

S Nazarnezhad, F Kermani, VR Askari… - Journal of …, 2022 - Elsevier
Skin defects are among the most prevalent and serious problems worldwide; it is necessary
to provide appropriate coverage in order to reduce possible mortality risk and accelerate …