[HTML][HTML] Associations of Chlamydia trachomatis serology with fertility-related and pregnancy adverse outcomes in women: a systematic review and meta-analysis of …

Y Zuo, TT Jiang, Y Teng, Y Han, YP Yin, XS Chen - EBioMedicine, 2023 - thelancet.com
Background Chlamydia trachomatis (CT) infection has an increased risk for fertility-related
and pregnancy adverse outcomes partly due to mechanisms related to a pro-inflammatory …

[HTML][HTML] The inclusion membrane protein IncS is critical for initiation of the Chlamydia intracellular developmental cycle

ME Cortina, RC Bishop, BA DeVasure… - PLoS …, 2022 - journals.plos.org
All Chlamydia species are obligate intracellular bacteria that undergo a unique biphasic
developmental cycle strictly in the lumen of a membrane bound compartment, the inclusion …

[HTML][HTML] Mast cells selectively produce inflammatory mediators and impact the early response to Chlamydia reproductive tract infection

A Mayavannan, E Shantz, ID Haidl, J Wang… - Frontiers in …, 2023 - frontiersin.org
Introduction Chlamydia trachomatis (C. trachomatis) is a Gram-negative obligate
intracellular bacterium that causes reproductive tract complications in women, including …

[HTML][HTML] The role of IL-17 during infections in the female reproductive tract

P Bagri, VC Anipindi, C Kaushic - Frontiers in Immunology, 2022 - frontiersin.org
Interleukin-17 (IL-17A) is a cytokine involved in a complex array of both protective and
detrimental processes. Although early biological studies focused on the pro-inflammatory …

[HTML][HTML] A novel multi-variate immunological approach, reveals immune variation associated with environmental conditions, and co-infection in the koala …

CM Fernandez, MB Krockenberger, Valentina… - Scientific Reports, 2024 - nature.com
External signs of disease are frequently used as indicators of disease susceptibility.
However, immune profiling can be a more effective indicator to understand how host …

A minimal replicon enables efficacious, species-specific gene deletion in Chlamydia and extension of gene knockout studies to the animal model of infection using …

KA Fields, MD Bodero, KR Scanlon… - Infection and …, 2022 - Am Soc Microbiol
The genus Chlamydia consists of diverse, obligate intracellular bacteria that infect various
animals, including humans. Although chlamydial species share many aspects of the typical …

Homologues of the Chlamydia trachomatis and Chlamydia muridarum inclusion membrane protein IncS are interchangeable for early development but not for …

ME Cortina, I Derré - Msphere, 2023 - Am Soc Microbiol
Chlamydia trachomatis is an obligate intracellular bacterium, which undergoes a biphasic
developmental cycle inside a vacuole termed the inclusion. Chlamydia-specific effector …

Neisseria gonorrhoeae Coinfection during Chlamydia muridarum Genital Latency Does Not Modulate Murine Vaginal Bacterial Shedding

D Onorini, CA Leonard, R Phillips Campbell… - Microbiology …, 2023 - Am Soc Microbiol
Chlamydia trachomatis and Neisseria gonorrhoeae are the most frequently reported agents
of bacterial sexually transmitted disease worldwide. Nonetheless, C. trachomatis/N …

A targeted approach to investigating immune genes of an iconic Australian marsupial

LW Silver, Y Cheng, BL Quigley, A Robbins… - Molecular …, 2022 - Wiley Online Library
Disease is a contributing factor to the decline of wildlife populations across the globe.
Koalas, iconic yet declining Australian marsupials, are predominantly impacted by two …

[HTML][HTML] Elimination of Chlamydia muridarum from the female reproductive tract is IL-12p40 dependent, but independent of Th1 and Th2 cells

JA Rixon, KD Fong, C Morris, AT Nguyen… - PLoS …, 2024 - journals.plos.org
Chlamydia vaccine approaches aspire to induce Th1 cells for optimal protection, despite the
fact that there is no direct evidence demonstrating Th1-mediated Chlamydia clearance from …