Body fluid-derived stem cells—an untapped stem cell source in genitourinary regeneration

RL Huang, Q Li, JX Ma, A Atala, Y Zhang - Nature Reviews Urology, 2023 - nature.com
Somatic stem cells have been obtained from solid organs and tissues, including the bone
marrow, placenta, corneal stroma, periosteum, adipose tissue, dental pulp and skeletal …

Urine-derived stem cells: Promising advancements and applications in regenerative medicine and beyond

Y Sun, H Zhao, S Yang, G Wang, L Zhu, C Sun, Y An - Heliyon, 2024 - cell.com
Currently, stem cells are a prominent focus of regenerative engineering research. However,
due to the limitations of commonly used stem cell sources, their application in therapy is …

In vivo safety and biodistribution profile of Klotho-enhanced human urine-derived stem cells for clinical application

SH Kim, SH Lee, JA Jin, HJ So, JU Lee, MJ Ji… - Stem Cell Research & …, 2023 - Springer
Background Urine-derived stem cells (UDSCs) can be easily isolated from urine and
possess excellent stem cell characteristics, making them a promising source for cell …

Development of renal fibrosis in patients with chronic kidney disease: Mechanisms, biomarkers, and clinical implications

L Denova - Ukrainian Journal of Nephrology and Dialysis, 2023 - ukrjnd.com.ua
CKD is a global health concern with significant implications for patients' well-being,
morbidity, and mortality. The underlying mechanism of CKD development often involves …

[HTML][HTML] Circ DENND4C inhibits pyroptosis and alleviates ischemia-reperfusion acute kidney injury by exosomes secreted from human urine-derived stem cells

B Yang, J Wang, J Qiao, Q Zhang, Q Liu, Y Tan… - Chemico-Biological …, 2024 - Elsevier
Acute kidney injury (AKI) is a disease characterised by acute onset, high mortality, and poor
prognosis, and is mainly caused by ischemia-reperfusion (I/R). Human urine-derived stem …

Fibrosis in Chronic Kidney Disease: Pathophysiology and Therapeutic Targets

AB Reiss, B Jacob, A Zubair, A Srivastava… - Journal of Clinical …, 2024 - mdpi.com
Chronic kidney disease (CKD) is a slowly progressive condition characterized by decreased
kidney function, tubular injury, oxidative stress, and inflammation. CKD is a leading global …

Urine-Derived Stem Cells Reverse Bleomycin‑Induced Experimental Pulmonary Fibrosis by Inhibition of the TGF-β1-Smad2/3 Pathway

Y Zhang, Y Xia, R Zhang, X Zhou, J Jiang - Cytotherapy, 2024 - Elsevier
Background Idiopathic pulmonary fibrosis (IPF) is characterized by progressive lung
interstitial lesions with the disease pathophysiology incompletely understood, which is a …