Enzyme immobilization has been developing since the 1960s and although many industrial
biocatalytic processes use the technology to improve enzyme performance, still today we …

The introduction of the E Factor in 1992 focussed attention on the problem of waste
generation, defined as everything but the desired product, in chemicals manufacture and …

Biocatalysis has an enormous impact on chemical synthesis. The waves in which
biocatalysis has developed, and in doing so changed our perception of what organic …

The market for industrial enzymes has witnessed constant growth, which is currently around
7% a year, projected to reach $10.5 billion in 2024. Lipases are hydrolase enzymes …

The covalent immobilisation of enzymes generally involves the use of highly reactive
crosslinkers, such as glutaraldehyde, to couple enzyme molecules to each other or to …

Catalytic enantioselective transformations provide well-established and direct access to
stereogenic synthons that are broadly distributed among active pharmaceutical ingredients …

How do you get into flow? We trained in flow chemistry during postdoctoral research and are
now applying it in new areas: materials chemistry, crystallization, and supramolecular …

Enzymes are outstanding (bio) catalysts, not solely on account of their ability to increase
reaction rates by up to several orders of magnitude but also for the high degree of substrate …

With the current pressing need to rise to the ambition of net zero targets to mitigate carbon
emissions and climate change impacts, sustainable processing has never been more …

In this Perspective we show how an expansion of the scope and impact of biocatalysis in
industrial organic synthesis is enabled by streamlining the underpinning biocatalyst and …